Protein Alignment CG12061 and Slc24a2

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_006538405.1
• Gene: Slc24a2 / 76376
• MGIID: 1923626
• Length: 746
• Species: Mus musculus
• Alignment Length: 665
• Identity: 157/665 - (23%)
• Similarity: 264/665 - (39%)
• Gaps: 251/665 - (37%)

  Fly     9 DFKPNGNEWEYYPFAYRHDMRYDIDARNCTLPAIVEFPNLM-----RQKSWIAIVVSTLVSMYLF 68
            |:.|.       |.|.:.|     .|.|.|.....::|..:     |:|.  ||::..:..:|:|
Mouse    97 DYTPQ-------PPASQED-----QAENSTEHTQGDYPKDIFSLEERRKG--AIILHVIGMIYMF 147

  Fly    69 VILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGS 133
            :.||||||::.||::..:...|.::.|||||||:||..||||||.:.:|.|:.:.::|:||||||
Mouse   148 IALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGS 212

  Fly   134 SVFNILVIAGVCGIFTQP-TKLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISY 197
            :|||||.:.|:|.:|::. ..|.|||:.||.::|::.:..|.....|:::||:|:..||..|.:|
Mouse   213 AVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAY 277

  Fly   198 VIQLSFDRRIQNLV--------------------------------------------------- 211
            |:.:.|:.:::..|
Mouse   278 VVFMKFNVQVERWVKQMISRNNVIKVTVPEAQAKLSEFPPASQADGRTACPTITNDPDCQSLCFE 342

  Fly   212 ------RH-------------EHAESELLDEDP--------------------MTREE------- 230
                  ||             |..::..::|.|                    .|.||
Mouse   343 VYPETARHGSCITNVNGEPLKEKTQNSCMEESPTAGDKDGPTLPVGSSSAACSCTSEECVAESKP 407

  Fly   231 ----------------------------EPL------------------KG-FRD-----HVCAK 243
                                        :||                  :| ||:     |..||
Mouse   408 RLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAK 472

  Fly   244 PKTEY------------------------------------------------------------ 248
            .|.:.
Mouse   473 KKCQVDENERQNGAANHVEKIELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAE 537

  Fly   249 -------------NFYQWTWWAIKYPAELMLACTV-----PSARSIFFLSMISAILWISLISYLL 295
                         |..:...:.|.:|....|..|:     |::|..|.::...:|.||::.|||:
Mouse   538 EEDDQPLSLSWPTNTRKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLM 602

  Fly   296 TWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGL 360
            .|:...:|..:.|.:.|||||:||||||:|::.:|.||::||.|.||:.:::|||.|||.|.|.|
Mouse   603 VWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPL 667

  Fly   361 PWLLKILIYQ-QKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIA 424
            ||||..:|:: ..:.:.|..|.....:|.:....:.|.:...::.|.|.:|::....|.:||:::
Mouse   668 PWLLYTIIHRFSPVTVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVS 732

  Fly   425 CTLEILLNKEKMCDI 439
            ..||   :|..:|.:
Mouse   733 VLLE---DKVLVCPV 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	139/589 (24%)
		Na_Ca_ex	62..199	CDD:279963	59/137 (43%)
		Na_Ca_ex	276..424	CDD:279963	54/148 (36%)
Slc24a2	XP_006538405.1	2A1904	<99..746	CDD:273344	156/663 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820