Protein Alignment CG12061 and slc24a5

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001025451.1
• Gene: slc24a5 / 570312
• ZFINID: ZDB-GENE-031210-1
• Length: 513
• Species: Danio rerio
• Alignment Length: 455
• Identity: 145/455 - (31%)
• Similarity: 242/455 - (53%)
• Gaps: 57/455 - (12%)

  Fly    28 MRYDID-ARNCTLPAIVEFPN---LMRQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCY 88
            :|.|:: |..|..|...|||.   .::::....|::..::..|:.:.::||||:|.:|::|.:..
Zfish    48 VRRDLENASECVQPQSSEFPEGFFTVQERKDGGILIYFMIIFYMLLSVSIVCDEYFLPSLEVISE 112

  Fly    89 TLRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQPT- 152
            .|.::.|||||||:||.:|||||...|:|.|||.||||:.||:||:|:|:|.|...||:.:...
Zfish   113 RLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIMGSAVYNLLCICAACGLLSSAVG 177

  Fly   153 KLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRHEHAE 217
            :|..||:.||...|.|::|::..::.|:.|.||:...|||:|..||..|.||.||...|....:.
Zfish   178 RLSCWPLFRDCVAYAISVAAVIAIISDNRVYWYDGACLLLVYGVYVAVLCFDLRISEYVMQRFSP 242

  Fly   218 S--ELLDEDPMTREEEPLKGFRD----HVCAKPKTEYNFYQ------------------------ 252
            .  .|...|..:.|::||.|:.|    .|..:.:.:...:|
Zfish   243 CCWCLKPRDRDSGEQQPLVGWSDDSSLRVQRRSRNDSGIFQDDSGYSHLSLSLHGLNEISDEHKS 307

  Fly   253 ----------WTWWAIKYPAELMLACTVPSAR-----SIFFLSMISAILWISLISYLLTWFLTIL 302
                      ...|.:..|...:|..:||..|     :.:.|:.:.:.:|||..:|:|.|.:||:
Zfish   308 VFSMPDHDLKRILWVLSLPVSTLLFVSVPDCRRPFWKNFYMLTFLMSAVWISAFTYVLVWMVTIV 372

  Fly   303 GYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKIL 367
            |..|.|||.:||:|:||||||:|:..:|.:|:::|...||:.|.:|||.||:| ||||||.::.:
Zfish   373 GETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDML-CLGLPWFIQTV 436

  Fly   368 IYQ--QKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLEIL 430
            ...  ..::::|:.|...:..|:::...|:|.:....:.:...:|.:.:..|.||    .||.||
Zfish   437 FVDVGSPVEVNSSGLVFMSCTLLLSIIFLFLAVHINGWKLNWKLGLVCLACYILF----ATLSIL 497

  Fly   431  430
            Zfish   498  497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	132/408 (32%)
		Na_Ca_ex	62..199	CDD:279963	59/137 (43%)
		Na_Ca_ex	276..424	CDD:279963	51/149 (34%)
slc24a5	NP_001025451.1	ECM27	81..497	CDD:223604	135/420 (32%)
		Na_Ca_ex	84..228	CDD:279963	61/143 (43%)
		Na_Ca_ex	346..497	CDD:279963	53/155 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	1	1.000	-	-		oto40719
orthoMCL	1	0.900	-	-		OOG6_106315
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820