DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12061 and slc8b1

DIOPT Version :9

Sequence 1:	NP_001104467.2	Gene:	CG12061 / 3354990	FlyBaseID:	FBgn0040031	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_021333605.1	Gene:	slc8b1 / 560601	ZFINID:	ZDB-GENE-130530-900	Length:	301	Species:	Danio rerio

Alignment Length:	190	Identity:	51/190 - (26%)
Similarity:	93/190 - (48%)	Gaps:	18/190 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PNLMRQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPE 110
            |:|:.    :||.:..:..::||::|.::..|:..|.:..:..|||:|::|||.||||....||:
Zfish    95 PSLLP----LAITIYVIWLLFLFLVLGLIASDFFCPNLSAIASTLRLTHNVAGVTFLALGNGAPD 155

  Fly   111 LFVNFVG-TFVTNGDIGLGTIVGSSVFNILVIAGVCGI---FTQPTKLDWWPVTRDTAWYLIAIA 171
            :|..... :......:.:|.:.|:.:|...|:||...:   ||..::    |..||..:|:.|:.
Zfish   156 VFSAMAAFSHPQTAGLAIGALFGAGIFVTTVVAGSVALVKPFTVASR----PFLRDVIFYMAAVF 216

  Fly   172 SLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRHEHAESELLDEDPMTREEE 231
            ....||:...:...|:...|.:||:||..:.....|.|..:|:      |.|.|.:.:.|
Zfish   217 WTFTVLYKGHISLGESVGYLGMYIAYVFTVILSSYIYNRQKHQ------LTESPQSSDRE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	47/175 (27%)
		Na_Ca_ex	62..199	CDD:279963	39/140 (28%)
		Na_Ca_ex	276..424	CDD:279963
slc8b1	XP_021333605.1	Na_Ca_ex	66..>246	CDD:332332	44/158 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910