Protein Alignment CG12061 and slc24a1

DIOPT Version :10

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_009291877.3
• Gene: slc24a1 / 558299
• ZFINID: ZDB-GENE-060503-191
• Length: 741
• Species: Danio rerio
• Alignment Length: 569
• Identity: 139/569 - (24%)
• Similarity: 234/569 - (41%)
• Gaps: 192/569 - (33%)

  Fly    50 RQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVN 114
            |:|.|:::.:..:|  |:||.||||||::.||.:..:...|.::.|||||||:||..||||||.:
Zfish   165 RRKGWVSLHIFGMV--YMFVSLAIVCDEFFVPTLGVITDKLAISDDVAGATFMAAGGSAPELFTS 227

  Fly   115 FVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-QPTKLDWWPVTRDTAWYLIAIASLTYVLW 178
            .:|.|:::.::|:||||||:|||||.:.|:|.:|: :...|.|||:.||.::|::.:..|.....
Zfish   228 LIGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSREMLHLTWWPLFRDVSFYILDLIMLIIFFL 292

  Fly   179 DSLVMWYEAFALLLLYISYVIQLSFDRRIQ-----NLVRHEHAESELLDEDP---------MTRE 229
            |:.:||:|:..|:..|..||..:.|:.:::     .|.:|:.....:..|:|         ..|.
Zfish   293 DNTIMWWESMMLVGGYALYVTFMKFNVQLERAFKSQLSKHKSIVKVIAVEEPEKDNGTSGEENRP 357

  Fly   230 EEP-------LK----------------------------------------------------G 235
            .||       ||                                                    .
Zfish   358 PEPEDKNRLKLKPTLQRGGSSASLHNSTMRNTIFQLMIHTLDPLGEESVFNGDAKARSSLECKVK 422

  Fly   236 FRDHV-----CAKPKTEYN---------------------------------------------- 249
            |:|..     .|:.|.|..
Zfish   423 FKDKAQILNDMARGKVENKKKEKSGEGDDQSEQTKDSKDAPPGAKDEDTNQKSEAQKDGDIAAGG 487

  Fly   250 ----------------------------------------------------FYQW-------TW 255
                                                                ..:|       ..
Zfish   488 GSENPGGSDNSGDDDEDDSDEESDDDDDDDDDDDDDDDENEDEAGEDGDEPLSLEWPDTRRKQAT 552

  Fly   256 WAIKYPAELMLACTVPSARS-----IFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGL 315
            :....|....|..|||..|:     .|.::.:.:|:||::.|||:.|:...:|..:.|.:.||||
Zfish   553 YLFLLPIVFPLWLTVPDVRNPASKKFFVITFLGSIVWIAIFSYLMVWWAHQVGETIGISEEIMGL 617

  Fly   316 TVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKILIYQ-QKIDIDSTA 379
            |:||||||:|::.:|.||::||.|.||:.:::|||.|||.:.|.:|||:....:. ..:.:.|..
Zfish   618 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITMGLPVPWLMFSFFHSFAPVPVSSNG 682

  Fly   380 LTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLE 428
            |.....:|.:....:.:.:.|.::.|.|.:|:...|.|.:||:::..||
Zfish   683 LFCAIVLLFLMLLFVIISIAACKWRMNKVLGFTMFILYFVFLVLSVMLE 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	133/550 (24%)
slc24a1	XP_009291877.3	None