Protein Alignment CG12061 and slc24a3

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_685302.4
• Gene: slc24a3 / 557196
• ZFINID: ZDB-GENE-090312-67
• Length: 660
• Species: Danio rerio
• Alignment Length: 596
• Identity: 180/596 - (30%)
• Similarity: 276/596 - (46%)
• Gaps: 189/596 - (31%)

  Fly     6 SSTDFKPNGNEWEYYPFAYRHDMRYDIDA-------------RNCTLPAIVEFP-NLMRQKSWI- 55
            |:.|.|    :||    :.|....:|||:             :|||.|.|.||| ::..|:..:
Zfish    66 SAEDSK----KWE----SRRLLQDFDIDSNYTDEVQLGPNADKNCTPPGIHEFPDDIFTQQERLE 122

  Fly    56 -AIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVNFVGTF 119
             |:.:..|.:||:|..||:|||||.||::|::|..|.::.|||||||:||.:||||||.:.:|.|
Zfish   123 GAVALHVLCAMYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVF 187

  Fly   120 VTNGDIGLGTIVGSSVFNILVIAGVCGIFT-QPTKLDWWPVTRDTAWYLIAIASLTYVLWDSLVM 183
            :|.||:|:||||||:|||||.|.||||||| |..:|..|.:.||:.:|.||:|:|...::|..|.
Zfish   188 ITKGDVGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 252

  Fly   184 WYEAFALLLLYISYVIQLSFDRRIQNLVR-----------------------------------H 213
            |:|:..|::||:.|::.:.|:.|:.:.:.                                   |
Zfish   253 WWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDIDDGCDATVVLLKKANFH 317

  Fly   214 EHAESELLDE------------------------DPMTR-------------------------- 228
            ......::||                        .|.||
Zfish   318 RKPSVLMVDELLSAYPHQLTFSEAGMRIMITSHFSPRTRLTMASRMLITERQRLINSRFSNGDSE 382

  Fly   229 -----------------------------------------------------------EEE--- 231
                                                                       |||
Zfish   383 VTVKMPGKRGVENGLAGPDRGLNGRKGGHHDDDRGGAEAGTDTENENEDNENNENDEEEEEEDEN 447

  Fly   232 --PLKGFRDHVCAKPKTEYNFYQWTWWAIKYPAELMLACTVPSARS-----IFFLSMISAILWIS 289
              |...||   |  |....|..:   |.:.:|..::|..|||::.:     .:.:|.||:.:||:
Zfish   448 EGPYVPFR---C--PGGGINKLK---WLLAWPLSMLLFFTVPNSANPRWERWYMVSFISSTIWIA 504

  Fly   290 LISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDI 354
            ..||::.|.:|::||.:.|||.|||:|.||||||||:..:|.||:::|.|.|||.|:||||.|||
Zfish   505 FFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDI 569

  Fly   355 LVCLGLPWLLKILI--YQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFY 417
            |:.|||||.|:.|.  |...|.::|..|..:..:|:.:..:..||:....:.:.|.:|:..::.|
Zfish   570 LIGLGLPWALQTLAINYGSTIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMY 634

  Fly   418 ALFLIIACTLE 428
            |:||..:..:|
Zfish   635 AVFLCFSILIE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	159/517 (31%)
		Na_Ca_ex	62..199	CDD:279963	74/137 (54%)
		Na_Ca_ex	276..424	CDD:279963	63/149 (42%)
slc24a3	XP_685302.4	TIGR00367	127..637	CDD:273039	158/517 (31%)
		Na_Ca_ex	128..270	CDD:279963	74/141 (52%)
		Na_Ca_ex	491..643	CDD:279963	63/151 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577440
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850