Protein Alignment CG12061 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 471
• Identity: 148/471 - (31%)
• Similarity: 244/471 - (51%)
• Gaps: 75/471 - (15%)

  Fly    33 DARNCTLPAIVEFPN--LMRQKSWI-AIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTY 94
            ::..|.:....|||.  ..:|:|.. .||:..|:.:|:.:.::||||.|.:|::|.:..:|.::.
Mouse    42 NSTQCAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLSQ 106

  Fly    95 DVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-QPTKLDWWP 158
            |||||||:||.:|||||...|:|.|:|.||||:.||:||:::|:|.|...||:.: ..:.|..||
Mouse   107 DVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVSTLSCWP 171

  Fly   159 VTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRH---------- 213
            :.||.|.|.:::.::..:::|:.:.|||...|||:|..||:.|.||..|.   ||
Mouse   172 LFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTIS---RHVMKTCSPCCP 233

  Fly   214 --EHAESELLDEDPMTREEEPLKGFRDH----VCAKPKTEYNFYQ-------------------- 252
              ..|..|.:       |::.|.|:.|.    :..:.:|:...:|
Mouse   234 CLARAMEERI-------EQQTLLGWEDESQLFIRRQSRTDSGIFQEDSGYSQLSLSLHGLSQVSE 291

  Fly   253 --------------WTWWAIKYPAELMLACTVPSAR-----SIFFLSMISAILWISLISYLLTWF 298
                          ..:|.:..|...:||.|.|..|     :.|.::...:.||||..:|:|.|.
Mouse   292 DPPSVFSMPEADLRRIFWVLSLPIITLLALTTPDCRRKFWKNYFVITFFMSALWISAFTYILVWM 356

  Fly   299 LTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWL 363
            :|:.|..|.|||.:||||:||||||:|:..:|.:|::||.|.|||.|.:|||.||:| ||||||.
Mouse   357 VTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDML-CLGLPWF 420

  Fly   364 LKILIYQQK--IDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACT 426
            :|.......  |:::|..||..|..|.::...|:|.:....:.:.:.:|.:.::.|.....::..
Mouse   421 IKTAFTNASAPIEVNSKGLTYITISLNISILFLFLAVHFNGWKLDRKLGVVCLVLYLGLATLSVL 485

  Fly   427 LEILL---NKEKMCDI 439
            .||.:   |:.:.|.:
Mouse   486 YEIGIIGNNRIRGCGV 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	136/418 (33%)
		Na_Ca_ex	62..199	CDD:279963	57/137 (42%)
		Na_Ca_ex	276..424	CDD:279963	57/149 (38%)
Slc24a5	NP_778199.2	Na_Ca_ex	72..216	CDD:279963	59/143 (41%)
		TIGR00367	77..477	CDD:273039	134/410 (33%)
		Na_Ca_ex	334..485	CDD:279963	57/151 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4530
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	1	1.000	-	-		oto93918
orthoMCL	1	0.900	-	-		OOG6_106315
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.730