Protein Alignment CG12061 and Slc24a4

DIOPT Version :10

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001388274.1
• Gene: Slc24a4 / 314396
• RGDID: 1305926
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 169/545 - (31%)
• Similarity: 263/545 - (48%)
• Gaps: 162/545 - (29%)

  Fly    34 ARNCTLPAIVEFP-----NLMRQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMT 93
            |:|||.|||.|||     |..||..  |:::..|.::|:|..|||||||:.||::|::|..|.::
  Rat    74 AKNCTDPAIHEFPTDLFSNKERQHG--AVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLS 136

  Fly    94 YDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-QPTKLDWW 157
            .|||||||:||.:|.||||.:.:|.|:|:||:|:||||||:|||||.|.||||:|. |..:|.||
  Rat   137 EDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWW 201

  Fly   158 PVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLV----------- 211
            .|.||:.:|.:::..|...::|..::|:|...|::||:.|::.:.::.::|...
  Rat   202 AVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLILIILYVFYILIMKYNMKMQTFFTTKQKSIANGN 266

  Fly   212 ----------------------------------------------------------------- 211
                                                                             
  Rat   267 PVSNELEDGNDLYDGSFDDPSVPLLGQVKEKPPYGKSPVVMVDEILSSSPPKFTFPEAGLRIMIT 331

  Fly   212 --------------------------------------RHEHAESELL----DEDPMTREE---- 230
                                                  |||:.|:..:    .|||...:|
  Rat   332 NKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPP 396

  Fly   231 ------EP-------LKGFRDHVCAKPKTEYNFYQW--TWWAIKYPAELMLACTVPSA-----RS 275
                  ||       |..|     :.|:.:.:..:|  ||     |...:|..|:|:.     ..
  Rat   397 PQPPPPEPESVETVFLSPF-----SMPEAKGDKAKWVFTW-----PLIFLLCVTIPNCSKPRWEK 451

  Fly   276 IFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGS 340
            .|.::.|:|.|||::.|||:.|.:||:||.|.|||.|||:|.||||||||:..:|.||:::|.|.
  Rat   452 FFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGD 516

  Fly   341 MAICNAIGSNTFDILVCLGLPWLLKILI--YQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRF 403
            ||:.|.||||.|||||.||:||.|:.::  |...:.|:|..|..:..:|:.:.|:..||:...::
  Rat   517 MAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKW 581

  Fly   404 VMGKTVGYLSIIFYALFLIIACTLE 428
            .:.:.:|...::.||:||..:..:|
  Rat   582 RLDRKLGIYVLVLYAVFLCFSIMIE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	153/505 (30%)
Slc24a4	NP_001388274.1	2A1904	<80..606	CDD:273344	164/537 (31%)