Protein Alignment CG12061 and ncx-9

DIOPT Version :10

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_504342.2
• Gene: ncx-9 / 182576
• WormBaseID: WBGene00003574
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 675
• Identity: 123/675 - (18%)
• Similarity: 214/675 - (31%)
• Gaps: 273/675 - (40%)

  Fly    24 YRHDMRYDIDARNCTLPAIVE-FP---------NLMRQKSW------------------------ 54
            |.:|..||..:...|..:|.: ||         ..:..|||
 Worm    23 YEYDQSYDYPSPGSTNFSIYDGFPFDEEMCSSEECLIDKSWTSEEKCEYIKCNQDSCEGGGYLTW 87

  Fly    55 --------------IAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAAS 105
                          |.|::..|..:.||||::.:.||:..||:..:...|||:..:||.||||..
 Worm    88 SHYVKCQYNIGVRVILIILGILYLIILFVIMSSIADDFFCPAISGIVSHLRMSESIAGVTFLAFG 152

  Fly   106 TSAPELFVNFVGTFVT---NGDIGLGTIVGSSVFNILVIAGVCGIFTQPTKLDWWPVTRDTAWYL 167
            ..||::|.:......|   ..|:.||.:.|:|:|...|:..:. |||:..|:...|..||..:|:
 Worm   153 NGAPDVFSSISSVLTTPKPKADLALGDLFGTSIFVTTVVLAII-IFTKSFKVAIIPTLRDLIFYM 216

  Fly   168 IAIASLT--YVLWDSLVMWYEA------------------------------------------- 187
            ..:|.:.  ::.:|.:.:|..|
 Worm   217 TTLAFIVFCFLKFDKIEVWMPATFLGIYGVYVVTVIILGIYRTHRKKRNLKKKNKELEDFLSRPS 281

  Fly   188 ---------------------FALLLLYISY-----------------------------VIQLS 202
                                 .||....|.|                             ::.|.
 Worm   282 SAASTTPIFGAMKLKEETISVSALFHFMIGYSQFIKNLTRANLKRTTNNNNNDNKNEKRGIVNLG 346

  Fly   203 F--------DRRIQNLVRHEHAESEL--------LD-EDPMTREEEPLKGFRDH----------- 239
            |        :|:|..:.:....|::|        || .|...|||:  .|:..|
 Worm   347 FSEPYSIPSERKISTIFKQNTFETDLESLESLADLDGSDDEGREEK--FGYAHHTVFTSHDQISL 409

  Fly   240 VCAKPK----TEYNFYQWTW--------W-----------------AIKYPAELMLACTVPS--- 272
            |.::.:    |.:..:.|.|        |                 .||.........||||
 Worm   410 VASEIEEIEITTWRSWDWVWDLFNHLKSWPSRDEFSEMNIFIKIVTVIKVVPVFFFKLTVPSNEM 474

  Fly   273 --ARSIFFLSMISAI--------------------LWI--------------------------- 288
              .:.:|.|...::|                    ||:
 Worm   475 SWCKPLFILHCFASIQFALFSIQIITLKPFDGSPGLWLYGLGFSAILAMVAMYFLPLSKEQKYYK 539

  Fly   289 SLISYL-----LTWF----------LTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGY 338
            .:.|||     :.|.          :|::|....:...::|||::|....:.::.:...|.|:||
 Worm   540 EIYSYLGFLMSIAWIYATSNEIVSVVTMIGVVTGLSMELLGLTIMAWSNCIGDIVADIAVVKQGY 604

  Fly   339 GSMAICNAIGSNTFDILVCLGLPWLLKILIYQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRF 403
            ..||:..|||...|::|:..|||:.:.....::...:.:....:....|.::....::.|..:||
 Worm   605 PKMAMAAAIGGPLFNLLIGFGLPFTIAAAQGKEMELLINPVYRLLMLFLGISLVTTFVALFIQRF 669

  Fly   404 VMGKTVGYLSIIFYALFLIIACTLE 428
            .:.:....|.|..:.:|||..|..|
 Worm   670 TVRRPHAVLLIFIFVVFLIFICLAE 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	106/582 (18%)
ncx-9	NP_504342.2	PLN03151	68..689	CDD:215604	109/623 (17%)