Protein Alignment CG12061 and ncx-8

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_504341.1
• Gene: ncx-8 / 182575
• WormBaseID: WBGene00003573
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 119/652 - (18%)
• Similarity: 215/652 - (32%)
• Gaps: 247/652 - (37%)

  Fly     5 WSSTD----FKPNGNEWE---YYPFAYRHDMRYDIDARNCTLPAIVEFPNLMRQKSWIAIVVSTL 62
            |:|.:    .|.|.:..|   |..:::....:|:|.||                  .:.|:|..:
 Worm    64 WTSEEKCAYIKCNQDSCEGGGYLTWSHYVKCQYNIGAR------------------VVLIIVGII 110

  Fly    63 VSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVNFVGTFVT---NGD 124
            ..::|||:::.:.||:..|::..:...|:|:..:||.||||....||::|.:......|   ...
 Worm   111 YLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSISSVLSTPKPKAA 175

  Fly   125 IGLGTIVGSSVFNILVIAGVCGIFTQPTKLDWWPVTRDTAWYLIAIASLT--YVLWDSLVMWYEA 187
            :.||.:.|:|:|...|:..:. |||:..|:...|..||..:|:|.:|.:|  ::.:|.:.:|..|
 Worm   176 LALGDLFGTSIFVTTVVLAII-IFTKSFKVAIIPTLRDLIFYMITLAFITFCFLKFDKIEVWMPA 239

  Fly   188 --FALLLLYISYVIQLSFDR-RIQNLVRHEHAESELLDEDPMTREEE-----PL----------- 233
              ..:..:|:..||..|..| |.:||.:.:..|||..||..::|.|.     |:
 Worm   240 TFLGIYAVYLLTVIAFSIYRTRRKNLKKKKQLESEKDDESAISRPESVASNMPICEKLEKKTESM 304

  Fly   234 -------------------------------------KGFRDHVCAK------------------ 243
                                                 :||.:.:.|.
 Worm   305 SVSTLFHVMVGLSRFMKKLNRTNKIQSIENKKQGFVNEGFSESLDADELTLKRNRMISLIFRNKT 369

  Fly   244 ------------------------------------------PKTEYNFYQWTWW---------- 256
                                                      ..||:.|.:.|.|
 Worm   370 LDTDLESMKTLDEMESSDDEGREEEFAYAHHTVFTSHDQMSLAATEFEFRELTTWRSRDWIIDLL 434

  Fly   257 -----------------------AIKYPAELMLACTVPS-----ARSIFFLSMISAI-------- 285
                                   .|:......:..|:||     .:.:|.|...::|
 Worm   435 YHLKPWPSREEFSEMNIFVKIIMIIRIIPSFFMKMTIPSNEMSWCKPLFLLHCFASIQFALFSIQ 499

  Fly   286 ------------LWI---------------------------SLISYL-----LTWF-------- 298
                        ||:                           .:.|||     :.|.
 Worm   500 IINLKPFDGSPGLWLYGLAFSATIALLALCFLPLNKELKYHKEVYSYLGFLMSIAWIYATANEII 564

  Fly   299 --LTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLP 361
              :|::|....:...::||||::....:.::.:...|.|:||..||:..|||...|::|:..|||
 Worm   565 SVMTMVGVVTGLSQELLGLTVMSWSDCIGDIVADIAVIKQGYPKMAMAAAIGGPLFNLLIGFGLP 629

  Fly   362 WLLKILIYQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACT 426
            :.:.....:|...|.:....|....|.::....::.|...||.:........|..:..|:|..|.
 Worm   630 FTIASAQGKQIDLIINPVYRILLLFLGISLVTTFVALFIERFTVRWPHAVALIFIFINFVIFVCL 694

  Fly   427 LE 428
            .|
 Worm   695 AE 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	104/581 (18%)
		Na_Ca_ex	62..199	CDD:279963	39/143 (27%)
		Na_Ca_ex	276..424	CDD:279963	39/209 (19%)
ncx-8	NP_504341.1	PLN03151	61..628	CDD:215604	104/582 (18%)
		Na_Ca_ex	107..253	CDD:279963	40/146 (27%)
		Na_Ca_ex	544..681	CDD:279963	31/136 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810