Protein Alignment CG12061 and slc24a2

DIOPT Version :10

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_031746284.1
• Gene: slc24a2 / 100494112
• XenbaseID: XB-GENE-483618
• Length: 701
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 142/576 - (24%)
• Similarity: 237/576 - (41%)
• Gaps: 197/576 - (34%)

  Fly    44 EFPNLM-----RQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLA 103
            |:|..:     |||.  |:::.....:|:|:.||:|||::.||::..:...|.::.|||||||:|
 Frog   122 EYPEDLFSLEERQKG--AVILHIFGMIYMFIALAVVCDEFFVPSLTVITEKLGISDDVAGATFMA 184

  Fly   104 ASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQP-TKLDWWPVTRDTAWYL 167
            |..||||||.:.:|.|:::.::|:||||||:|||||.:.|:|.:|::. ..|.|||:.||.::|:
 Frog   185 AGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSKEILNLTWWPLFRDVSFYI 249

  Fly   168 IAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVR-------------------- 212
            :.:..|.....|:.:.|:|:..||:.|:.||..:.::.:::|.|:
 Frog   250 VGLIMLITFFLDNFIQWWESLLLLVAYLMYVTFMKYNVQVENFVKRKINRNKVVKVPSANTDGKD 314

  Fly   213 -------------HE-------------------------------------------------- 214
                         ||
 Frog   315 QPNILVESRVPPEHEGVAMDIRHGELNETAGLKETWTETATSPGKTKPRLQRGGSSASLHNSLMR 379

  Fly   215 --------HAESELLDE----------DPMTREEEPLKGFRD-----HVCAKPKTEYNFYQWTWW 256
                    |....|.:|          |.||.|.:    ||:     |..||.|.:....:....
 Frog   380 NSIFQLMIHTLDPLSEEIGAYGKLKYYDTMTEEGK----FREKASILHKMAKKKCQVEDSERLNG 440

  Fly   257 AIKY-----------------------------------------------------PAELMLAC 268
            |..|                                                     |..|....
 Frog   441 AASYTEKVDLPNTANVEFEVTPPKESTGPVQNGNVSHNTEAGETQIPAAEQTEEDDQPLSLAWPT 505

  Fly   269 TV-------------------------PSARSIFFLSMISAILWISLISYLLTWFLTILGYNLNI 308
            |:                         |::|..|.::...:|.||::.|||:.|:...:|..:.|
 Frog   506 TIRKQAAYLAVLPIVFPLWVTLPDVRNPNSRKFFPVTFFGSITWIAVFSYLMVWWAHQVGETIGI 570

  Fly   309 PDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKILIYQQ-K 372
            .:.|||||:||||||:|::.:|.||::||.|.||:.:::|||.|||.|.|.:||||..:.:.. .
 Frog   571 TEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPMPWLLYSVSHNMIP 635

  Fly   373 IDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLE 428
            :.:.|..|.....:|.:....:.|.:...::.|.|.:|......|.:||:::..||
 Frog   636 VAVSSNGLFCAIVLLFIMLLFVILSIAFCKWKMNKILGCTMFGLYFVFLVVSVLLE 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	133/546 (24%)
slc24a2	XP_031746284.1	2A1904	<120..701	CDD:273344	142/576 (25%)