Protein Alignment tyn and MATN4

DIOPT Version :9

• Sequence 1: NP_001027032.1
• Gene: tyn / 3354987
• FlyBaseID: FBgn0284435
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001380459.1
• Gene: MATN4 / 8785
• HGNCID: 6910
• Length: 581
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 95/513 - (18%)
• Similarity: 153/513 - (29%)
• Gaps: 176/513 - (34%)

  Fly     4 TQSKSDRSSMHRGPLLLCAVMVVLVTLPEQINARMAFEKLTDFDF---------PGNT-----YY 54
            ||.:......|.|||.|    |.::.....:.. ..||.:..|..         |..|     .|
Human    19 TQLQLTGPRCHTGPLDL----VFVIDSSRSVRP-FEFETMRQFLMGLLRGLNVGPNATRVGVIQY 78

  Fly    55 SVKNLSLYECQGWCREEADCQAAAFSFVVNPLSPSQETHCQLQNDSSAANPSAAPQRSANMYYMI 119
            |.:..|::..:.:.|.| |.:.|....|  ||:....|...:|...:.|...|...|...
Human    79 SSQVQSVFPLRAFSRRE-DMERAIRDLV--PLAQGTMTGLAIQYAMNVAFSVAEGARPPE----- 135

  Fly   120 KLQLRSENVCHRPWSFERVPNKVI--------------------RGLDNALIY--------TSTK 156
                            ||||...:                    ||::   ||        ..:.
Human   136 ----------------ERVPRVAVIVTDGRPQDRVAEVAAQARARGIE---IYAVGVQRADVGSL 181

  Fly   157 EACLSACLNERRFVCRSVE------YDYNNMKCVLSDSDRRSSGQFVQLVDAQGTDYFENLCL-- 213
            .|..|..|:|..|:..|.:      ..:.:..|.:.             :.|:||...|:.|:
Human   182 RAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAID-------------LCAEGTHGCEHHCVNS 233

  Fly   214 ---------------KPAQACK--NNRSFGNSQKMGVSEEKVAQYVG--LHYYTDKELQVTSES- 258
                           :..::|:  :..||||.   ....|.|:...|  .|.....:||....|
Human   234 PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNH---SCQHECVSTPGGPRCHCREGHDLQPDGRSC 295

  Fly   259 -----------ACRLACEIES---EFLCRSFLYLGQPQGSQY--------NCRLYHLDHKTLPDG 301
                       .|...|..|.   ..||        |:|.|.        .||..|:|...|.||
Human   296 QVRDLCNGVDHGCEFQCVSEGLSYRCLC--------PEGRQLQADGKSCNRCREGHVDLVLLVDG 352

  Fly   302 PST-----------YLNHERPLID---HGEPIG-QYFENQCEKAAGLGAGSPPGTLDKIDTLPVS 351
            ..:           ::|.....:|   .|..:| ..|.::......||.   .||..::....::
Human   353 SKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR---YGTAAEVKQAVLA 414

  Fly   352 LDTIEDPNLTNLTRNDVNCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNGRIYALGRSE 409
            ::.:|...:|.|....:          |.....:.:.|.....|.|..|.::..|||:
Human   415 VEYMERGTMTGLALRHM----------VEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052	14/64 (22%)
		PAN_AP_HGF	131..210	CDD:238532	18/112 (16%)
		PAN_1	236..327	CDD:394981	27/130 (21%)
		ZP	382..598	CDD:214579	7/28 (25%)
MATN4	NP_001380459.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000