DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and matn1

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001025613.1	Gene:	matn1 / 595001	XenbaseID:	XB-GENE-957559	Length:	490	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	50/275 - (18%)
Similarity:	101/275 - (36%)	Gaps:	83/275 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 TYYSVKNLSLYECQGWC-------REEADCQAAAFSFVVNPLSPSQET-HCQ----LQNDSSAAN 104
            :|..::.||....:.:|       ..:.||:....|      :|...| .|:    |..|....|
Frog   202 SYSLIEKLSKKFQEAFCVTADLCSTGDHDCEQICVS------TPGSYTCACRDGFTLNEDGKTCN 260

  Fly   105 PSAAPQRSANMYYMIKLQLRSENVCHRPWSFERVP---NKVIRGLD-------NALI-------- 151
            ...|  .:.::.::|.   .|::|  ||.:||.|.   |:::..:|       ..|:
Frog   261 ACGA--SAVDLVFLID---GSKSV--RPENFELVKQFINQIVESMDVGDHRAHVGLVQYSSSVRQ 318

  Fly   152 ------YTSTKEACLSACLNERRFV------CRSVEYDYNNMKCVLSDSDRRSSGQFVQLVDAQG 204
                  |||.|:  :.:.:.:..::      .::::|..:|...:.|..........:...|.:.
Frog   319 EFPLGRYTSKKD--IKSAVKKMSYMEKGTMTGQALQYLIDNSFAISSGGRPAVPKVGIVFTDGRS 381

  Fly   205 TDYFENLCLKPAQACKNNRSF----GNS---QKMGVSEEKVAQYVGLHYYT---------DKELQ 253
            .||..:..|:..:.  ..:.|    ||:   :...::.|.|.::   .:||         .|:||
Frog   382 QDYINDAALRAKEL--GYKMFAVGVGNAVEEELRMIASEPVVEH---SFYTADFKAMKEIGKKLQ 441

  Fly   254 V---TSESACRLACE 265
            :   ..|:.|.  ||
Frog   442 MKICVEENPCE--CE 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052	10/56 (18%)
		PAN_AP_HGF	131..210	CDD:238532	18/108 (17%)
		PAN_1	236..327	CDD:394981	11/42 (26%)
		ZP	382..598	CDD:214579
matn1	NP_001025613.1	vWA_Matrilin	35..258	CDD:238752	12/61 (20%)
matn1	NP_001025613.1	vWFA	265..489	CDD:381780	36/204 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000