DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tyn and qsm

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001286637.1	Gene:	qsm / 47065	FlyBaseID:	FBgn0028622	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	91/360 - (25%)
Similarity:	149/360 - (41%)	Gaps:	79/360 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 VHCKDTRIAVQV-----RTNKPFNGRIYALG----RSETCNIDVINSDA-FRLDLT---MAGQDC 432
            |||.:.::.|.:     .:......:||..|    ..|.|...:..|.| |||.|:   ..|...
  Fly    29 VHCSEDQMRVDIGLPDAESKDQSAPQIYLEGLKGYPDERCQPQIDGSLAVFRLSLSDFYECGVTR 93

  Fly   433 NTQSVTG--VYSNTVVLQHHSVVMTKADKIYKVKC--------------TYDMSSKNITFG---- 477
            ....:||  ||.:.::::     .|...:|..|||              |...||.:.:.|
  Fly    94 MVNQLTGKKVYYHKIIIE-----STSGKEIVSVKCITTASPAYNVMMNATTGSSSTSTSSGGIHG 153

  Fly   478 -----MMP--IRDPEMIHINSS--PEAPPPRIRILDTRQ-----REVETVRIGDRLNFRIEIPED 528
                 ::|  .::||.:.|.:|  ..||.||:.|..::.     |:: ||:.|..|...|.:.||
  Fly   154 LVKRDVLPAGFQEPEDLEITTSLTKRAPEPRLSIGVSQDGQKFTRDL-TVKSGTPLTMEINLDED 217

  Fly   529 TP--YGIFARSCVAMAKDARTSFKIIDDDGCPTDPTIFPGF-TADGNALQSTYEAFRFTESYGVI 590
            :.  ||:...  .....|..||.:.:...||..||.:|..| |.||:.|.:.::||:|.:|..|.
  Fly   218 SAPVYGLGVN--YLDVTDTHTSSETLIFKGCTVDPYLFENFNTIDGDILSAKFKAFKFPDSSYVQ 280

  Fly   591 FQCNVKYCLGPCEPAVCEWNMDSFESLGRRRRRSIESNDT---------KSEDDMNISQ-EILVL 645
            |:..|..||..|....|..|...|   |||:|....:|..         :.:|...::: |:|.|
  Fly   281 FRATVNVCLDKCLGTQCSNNQVGF---GRRKREISSANKVYEISLAMFLQVQDIEGVNKNEVLQL 342

  Fly   646 DFGDEKREFFKADPST------DFAKDKTVTIIEP 674
            :  ::.||...|:...      :||.::|....:|
  Fly   343 E--EKLRELKLANQRLARNSRGNFAMEQTPASAQP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	68/265 (26%)
qsm	NP_001286637.1	ZP	30..298	CDD:214579	71/275 (26%)
qsm	NP_001286637.1	Zona_pellucida	<200..300	CDD:278526	33/102 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910