DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and Matn4

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001100009.1	Gene:	Matn4 / 296358	RGDID:	1309732	Length:	624	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	64/287 - (22%)
Similarity:	91/287 - (31%)	Gaps:	96/287 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KEACLSACLN-ERRFVCRSVEYDY----NNMKCVLSDSDRRSSGQFVQLVDAQGTDYFENLCLKP 215
            :..|...|:| ...|.| :....|    :|..|:..|            :.|:||...|:||:..
  Rat   225 EHGCQHLCVNAPGTFYC-ACNSGYKLAPDNRNCLAID------------LCAEGTHGCEHLCVSS 276

  Fly   216 AQA--CKNNRSFGNSQKMGVSEEKVAQYVGLHYYTDKELQVTSESACRL---------ACEIESE 269
            ..:  |:....|...|                          .:.:||.         :|:.|
  Rat   277 VDSYFCRCRAGFALQQ--------------------------DQRSCRAIDYCSFGNHSCQHE-- 313

  Fly   270 FLCRSFLYLGQPQGSQYNCRLYHLDHKTLPDGPSTYLNHERPLIDHGEPI-----GQYFENQCEK 329
              |.|.|.     |.|..||   ..|..||||.|..:......:|||...     |..|...|.:
  Rat   314 --CVSTLV-----GPQCRCR---EGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLSFHCLCPE 368

  Fly   330 AAGLGAGSPPGTLDKIDTLPVSLDTIED------PNLTNLTRNDVNCDKTGTCYDVSVHCKDTRI 388
            ...|.|...  :.|:.....|.|..:.|      |....|.:..||  :.....|||.  :.||:
  Rat   369 GRRLQADGK--SCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVN--QIVDFLDVSP--EGTRV 427

  Fly   389 AV-----QVRTNKPFNGRIYALGRSET 410
            .:     :|||..|       |||..|
  Rat   428 GLVQFSSRVRTEFP-------LGRYGT 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532	12/58 (21%)
		PAN_1	236..327	CDD:394981	22/104 (21%)
		ZP	382..598	CDD:214579	10/34 (29%)
Matn4	NP_001100009.1	vWA_Matrilin	33..255	CDD:238752	7/30 (23%)
		FXa_inhibition	262..297	CDD:291342	9/60 (15%)
		FXa_inhibition	303..338	CDD:291342	14/46 (30%)
		FXa_inhibition	344..379	CDD:291342	8/36 (22%)
		vWFA	385..621	CDD:294047	20/74 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000