DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cutl-19

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_871693.1	Gene:	cutl-19 / 191090	WormBaseID:	WBGene00022533	Length:	237	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	47/223 - (21%)
Similarity:	81/223 - (36%)	Gaps:	58/223 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   463 VKCTYD--MSSKNITFGMMPIRDPEMIHINSS--PEAPPPRIRIL------DTRQREVETVRIGD 517
            :||.|.  |:.|   .|:. :....||:.|.:  .....||.|:.      |.........::.|
Worm    18 IKCEYSELMNQK---IGVR-VEVLNMIYENETTITSTGHPRCRLTLHKSGWDRDTCSSPQFKLND 78

  Fly   518 RLNFRIE-----IPEDTPYGIFARSCVAMAKDARTSFKIIDDDGCPTDPTIF--PGFTADGNALQ 575
            .|::...     :.:.|.|.:...||  .......|..|:.||||..:..|.  |.:|:...|..
Worm    79 TLSWSTRVCYKWVCDTTKYAMRVESC--WIGSPNMSVYILRDDGCTIEKAILTSPVYTSFNRAAA 141

  Fly   576 STYEAFRFTESYGVIFQCNVKY------------CLGPCE----PAVCEWN-MDSFESL--GRRR 621
            ..:.|.|         |.|:||            |...|:    |..|..| .|.:|::  ...|
Worm   142 IGWMAVR---------QKNMKYMHVGCTIRLCHLCDPKCQTITPPRTCNDNRADDYEAMWNSSSR 197

  Fly   622 RRSIESNDTKSEDDMNISQEILVLDFGD 649
            .:::...:..:.:::|       |:||:
Worm   198 VKNLCFPEPSTTENLN-------LNFGN 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	35/163 (21%)
cutl-19	NP_871693.1	ZP	<17..171	CDD:214579	36/167 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910