DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tyn and cutl-4

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_507484.3	Gene:	cutl-4 / 189246	WormBaseID:	WBGene00012304	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	77/340 - (22%)
Similarity:	139/340 - (40%)	Gaps:	62/340 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 KTGTCYDVSVHCKDTRIAVQVRTNKPFNGRIYALG---RSETCNIDVINSDAFRLDLTM-AGQDC 432
            :.|...:..|.|...:|.:.:||::.|.|.:|:.|   :|| |.:.. ||.|..:::.: ...||
Worm    25 QNGIVGEPEVICDIKQIRITMRTSQSFIGNLYSKGFFHKSE-CRVRG-NSTANSIEIVLPVDSDC 87

  Fly   433 NTQ-----SVTGVYSNT-VVLQHHSVVMTKADKIYKVKCTYDMSSKNIT----FGMMPIRD-PEM 486
            ..:     :..|:..:| |:|..|.|.:|:.|:.|.|:|.|..|.:.:|    ..|.|..: |:.
Worm    88 GIRRKRMMNPRGILLDTIVILMFHPVFLTQTDRSYHVQCQYTESERTVTNALDVSMQPASELPQS 152

  Fly   487 IHINSSPEAPPPRIRIL--DTRQREVETVRIGDRLNFRIEIPEDTP--YGIFARSCVAMAKDART 547
            |...:...||..:..:|  :.:...:....:||.:..:.....:..  |.:...|||.   |...
Worm   153 IQQLNDDSAPVCKYEVLMENAQGPPLSHATVGDLVYHKWSCDGNNKEMYCMTVHSCVV---DDGQ 214

  Fly   548 SF--KIIDDDGCPTDPTIFPGFTADGNALQS--TYEAFRFTESYGVIFQCNVKY---------CL 599
            .|  |::|:.||..|..|......:...|::  ....|:|.:...|.|.|.::.         |:
Worm   215 GFGQKLVDEHGCTLDAFILKELEYNEKELEAGQMSSVFKFADKPTVFFSCMIRVEMKESAEMPCV 279

  Fly   600 GPCEPAVCEWNMDS--FESLGRRRRRSIE----------SNDTKSEDDMNISQEILVLDFGDEKR 652
            .|.|  ||: |:.|  .::|.....|.:.          .|:||.:.....|.:.:..:
Worm   280 IPTE--VCK-NLPSSKMQNLDVMTDRKVSDDIPPGFPRPQNNTKLQKSQKFSTDAMTSN------ 335

  Fly   653 EFFKADPSTDFAKDK 667
                :|.|.||..|:
Worm   336 ----SDYSADFLDDE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	57/247 (23%)
cutl-4	NP_507484.3	ZP	35..278	CDD:214579	57/247 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910