DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tyn and cutl-12

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001309578.1	Gene:	cutl-12 / 188735	WormBaseID:	WBGene00011928	Length:	569	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	75/337 - (22%)
Similarity:	127/337 - (37%)	Gaps:	63/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 VHCKDTRIAVQVRTNKPFNGRIYALG--RSETCNIDV---INSDAFRLDLTMAGQDCNTQSVTGV 440
            :.|....|.:.:.....|.|.:|..|  ....|:::.   :.:....:||...| .||.:....|
Worm    36 LECGSEGIRLHINPTGTFGGHVYVRGFFPQTVCHLNYCTRLTNRPIVMDLPFRG-PCNVRRRRNV 99

  Fly   441 ------YSNTVVLQHHSVVMTKADKIYKVKCTYDMSSKNITFGMMPIRDPEMIHINSSP------ 493
                  |..||::|||.:.:|..||.|::.|.|......:         .:.|:::..|
Worm   100 APPSISYDVTVIIQHHPLFVTSFDKAYRLNCIYRQQESTL---------QQRINVSDIPSTALQS 155

  Fly   494 -EAPPPRIRIL--DTRQREVETVRIGDRLNFRIEIPEDTPYGIFARSCVAMAKDARTSFKIIDDD 555
             .||..|..:|  ......|....:||.:..:.....|. :|....|||...:..: .|:.||:.
Worm   156 KNAPKCRYDVLSGSLNGPVVRFANVGDVVVHKWTCDSDR-FGFVVHSCVVRDESGK-DFQFIDER 218

  Fly   556 GCPTDPTIFP--GFTADGNALQSTYEAFRFTESYGVIFQCNVKYCL---GPCE---PAVCEWNMD 612
            ||.||.::||  .::.|..:..:...|||:.:...|.|.|.:..|.   ..||   |.:|. .||
Worm   219 GCVTDFSLFPEVSYSDDLKSAFTAVRAFRYADQVMVHFSCQITTCQKQENGCEGISPPICR-PMD 282

  Fly   613 SFESLGRRRRRSI--ESNDTKSEDDMNISQEILVLDFGDEKREFFKADPSTDFAKDKTVTIIEPC 675
                ||..:...:  |.|..|.::...:  |.|              .|.|:...:.:.|.:...
Worm   283 ----LGPIKVHYVKHEKNGEKFDEGGGV--ETL--------------PPRTENTSEGSTTTVRST 327

  Fly   676 PTKTSVLALAVT 687
            .|:....|.:.|
Worm   328 TTRERAQAFSTT 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	55/237 (23%)
cutl-12	NP_001309578.1	ZP	37..281	CDD:214579	60/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910