DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cutl-7

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001361852.1	Gene:	cutl-7 / 186153	WormBaseID:	WBGene00009961	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	322	Identity:	78/322 - (24%)
Similarity:	127/322 - (39%)	Gaps:	68/322 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 TGTCYDV--------SVHCKDTRIAVQVRTNKPFNGRIYALGRSETCNIDVINSDAFR--LDLTM 427
            |.:|:::        .|.|....|.|:|.|..|||||||..|.|:..:....::||..  .:.|:
Worm    18 TSSCFEIQNGVVGKPEVFCGIDTIRVKVNTEHPFNGRIYVDGESDKQHCVQHSADAHSSPQEFTI 82

  Fly   428 AGQDCN-----TQSVTGV-YSNTVVLQHHSVVMTKADKIYKVKCTYDMSSK----NITFGMMPIR 482
            ....||     |....|: :|.|::...|...:|..|:.:.::|.:..|.|    .|..|.:.
Worm    83 PIGACNMRRQRTLHPRGISFSFTMITSFHPFFVTGMDRAFSIRCFFLESIKGLNAEIDVGTLA-- 145

  Fly   483 DPEMIHINSSPEAPPPRIRILDTRQREV-ETVRIGDRLN--FRIEIPEDTPYGIFARSCVAMAKD 544
             |:  |::.....|.....:.|..:..| ...::|.::.  :|.:......|||...||  .|.|
Worm   146 -PQ--HVDQEYSLPVCAYHLKDGIEGHVLRFAQVGQKVTHVWRCDQDASHVYGILIHSC--YADD 205

  Fly   545 AR-TSFKIIDDDGCPTDPTIFPGFTADGNALQSTYEA--FRFTESYGVIFQCNVKYCL---GPCE 603
            .. ..|:::||.||.|||.:.|....:..|:.:...|  |::.:...:.|.|.|:.|.   |.||
Worm   206 GHGNKFELVDDRGCSTDPFLLPQIEYEHGAISAYTNAHVFKYADKVQLYFTCTVQLCYKHDGGCE 270

  Fly   604 ---PAVCEWNMDSFESLGRRRRRSIESNDTKSEDDMNISQEILVLDFGDEKREFFKADPSTD 662
               |..|     |..|.|.|..:                        |..:.:|...:|.||
Worm   271 GITPPQC-----SGHSHGIRGSK------------------------GPAEHKFVNLEPETD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	60/233 (26%)
cutl-7	NP_001361852.1	ZP	36..278	CDD:214579	66/253 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910