DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and F52C9.5

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001367876.1	Gene:	F52C9.5 / 186097	WormBaseID:	WBGene00018675	Length:	645	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	42/182 - (23%)
Similarity:	72/182 - (39%)	Gaps:	37/182 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ADCQAAAFSFVVNPLSPSQETHCQLQNDSSAA--NPSAAP-------QRSANMYYMIKLQLRSEN 127
            |:|..|.....:|.::...::...|.:.|:.|  :.:|.|       ||....|:        |.
Worm   311 AECAKACIENKINGVALKCKSFDFLSSTSTCAFTSEAAVPVGNGQLKQREDASYH--------EK 367

  Fly   128 VC-------HRPWS-FERVPNKVIRGLDNALIYTSTKEACLSACLNERR---FVCRSVEY--DYN 179
            :|       ..|.: |.|.|..::.|...::..:.:.|.|...|||..:   |.|.|..|  :.|
Worm   368 ICVSKSFVESCPSTFFSRHPQMILVGFAESVSDSPSFEHCFDTCLNSYQLFGFNCTSGMYYFEEN 432

  Fly   180 NMKCVLSDSDRRSSGQFVQLVDAQGTDYFENLCLKPAQACKNNRSFGNSQKM 231
            .:.|:|:..:|.:..:.....:....||||..|..|       ||..:.:||
Worm   433 QLNCILNSENRNTQRELFTEENTDIVDYFEVECTTP-------RSKQSKRKM 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052	4/24 (17%)
		PAN_AP_HGF	131..210	CDD:238532	21/84 (25%)
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579
F52C9.5	NP_001367876.1	PAN_AP	132..213	CDD:214680
		PAN_1	287..369	CDD:394981	13/65 (20%)
		PAN_AP_HGF	383..462	CDD:238532	19/78 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100