DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cut-4

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_496242.2	Gene:	cut-4 / 184037	WormBaseID:	WBGene00008482	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	53/245 - (21%)
Similarity:	94/245 - (38%)	Gaps:	51/245 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 VHCKDTRIAVQVRTNKPFNGRIYALG---------------------RSETCNIDVINSDAFRLD 424
            |.|:...|::..:|...|||:::..|                     |.::|.:.
Worm    41 VVCETASISLLFKTRNSFNGKVFVKGYVSEPSCMTVGDGKTGHRFEVRHDSCGVR---------- 95

  Fly   425 LTMAGQDCNTQSVTG-VYSNTVVLQHHSVVMTKADKIYKVKCTYDMSSKNITFGMMPIRDPEMIH 488
                    ..:.:.| |.|.||::..||:.:||.|:.|:|.|.|...:|.: ...:.|.......
Worm    96 --------RQREINGVVISATVIISFHSIFITKIDRAYRVSCFYVEGTKKV-HNHVDISALTTQL 151

  Fly   489 INSSPEAPPPRIRIL-DTRQREVETVRIGDRLNFR----IEIPEDTPYGIFARSCVAMAKDARTS 548
            :.|..:.|..|..|| :.....::..||||::..:    .|:  :..|.:...||..........
Worm   152 LESETQLPVCRYEILNEAGGSPIKYARIGDQVYHKWTCVAEL--ENVYCMKVHSCTVYDGQGGPP 214

  Fly   549 FKIIDDDGCPTDPTIFPG--FTADGNALQSTYEAFRFTESYGVIFQCNVK 596
            ..:||.:||..|..|...  :|:|..| ......|:|.:..|:.|.|.::
Worm   215 VTVIDANGCSVDGVILQNLEYTSDLTA-GKLAPVFKFADKAGLYFNCQIQ 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	52/244 (21%)
cut-4	NP_496242.2	ZP	43..283	CDD:214579	52/243 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910