DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cutl-14

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_492780.2	Gene:	cutl-14 / 182018	WormBaseID:	WBGene00015231	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	72/279 - (25%)
Similarity:	115/279 - (41%)	Gaps:	50/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 PGTL---DKIDTLPVSLDTIEDPNLTNLTRNDVNCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNG 400
            ||.|   .:|..:|:       ||              |...:|.|.|.||.|.....|...|.|
Worm     7 PGFLLFFHQISAIPI-------PN--------------GLLGNVEVECTDTTIEAVFLTETNFLG 50

  Fly   401 RIYALGRSETCNIDVINSDAFR--LDLTMAGQDCNTQSV-----TGVYSN-TVVLQHHSVVMTKA 457
            |::.||.|:  :.|.::.:..|  ..:|:....|..::|     .|..|: .:|:..|...:||.
Worm    51 RVFVLGHSQ--DKDCVSRETGRRTTSITVPRDKCGVETVQHGKGAGYTSSVNIVISFHDKFLTKV 113

  Fly   458 DKIYKVKCTY----DMSSKNITFGMMPIRDPEMIHINSSPEAPPPRIRILDTR-QREVETVRIGD 517
            |:.|.:.|.|    |:.|..:|.....::|.:::     .|.|.....:.|.| :|..|.|.:..
Worm   114 DRAYNITCLYAPTGDVVSYALTVQPSLLKDIQVL-----AEQPSCEYEVFDVRTRRPAEIVHVNA 173

  Fly   518 RLNFRIEIPEDTPYGIF---ARSCVAMAKDARTSFKIIDDDGCPTDPTIFPGFTADGNALQSTY- 578
            .|. .:...:.|...:|   ...||.....::...||||.:||..|.|..|....:.|.|.:..
Worm   174 PLE-HVWTCDGTNLDLFCMTVHDCVINEGKSKRRSKIIDSEGCSLDTTRLPNLRYENNKLSARVM 237

  Fly   579 -EAFRFTESYGVIFQCNVK 596
             :||||.:...|.|:|||:
Worm   238 SKAFRFGDDVAVEFECNVR 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	62/233 (27%)
cutl-14	NP_492780.2	ZP	32..270	CDD:214579	62/233 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910