DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and ZC449.1

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_508855.1	Gene:	ZC449.1 / 180775	WormBaseID:	WBGene00022611	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	306	Identity:	60/306 - (19%)
Similarity:	109/306 - (35%)	Gaps:	95/306 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 RSANMYYMIKLQLRSENVCHRPWSFERVPNKVIRGLD--NALIYTSTKEA-CLSACLNER----- 167
            ::::.||::                  |.|:::..:.  :..:|...::. |...|...:
Worm   213 KTSSGYYVV------------------VGNEIVLPISGGDVQVYNEVEQGDCAKYCSENKGPDGS 259

  Fly   168 RFVCRSVEYDYNNMKCVLSD--SDRRSSGQFVQLVDAQGTDYFENLCLKPAQ-ACKNNRSFGNSQ 229
            ...|||:.|.....||.|..  ::...||   :|::.:...|.|..||..:. .|:|:..|
Worm   260 TINCRSLNYFPVEKKCELYGILAEPHGSG---KLLENEKVIYAEKFCLPESPFVCQNDEIF---- 317

  Fly   230 KMGVSEEKVAQYVGLHYYTDKELQVTSESA-----CRLACEIESEFLCRSFLYLGQPQGSQYNCR 289
                       .:.:.....|..::|:::|     |...|..:.:  |||.:|:...:    .|.
Worm   318 -----------ILHVQKTLSKRRRITTKAASSITDCLRKCLEQDD--CRSSVYISNSK----KCE 365

  Fly   290 LYHLDHKTLPDGPSTYL---NHERPLIDHGEPIGQYFENQCEKAAGLGAGSPPGTLDKIDTLPVS 351
            |:::|..|     ..|.   :.|..||          ||.|.:     .|..|...|. .:|...
Worm   366 LHNVDVST-----GDYARDSDRETVLI----------ENGCRR-----KGVTPKRKDS-PSLSSI 409

  Fly   352 LDTIEDPNLTNLTRND--VNCDKTGTCYDVSVHCKDTRIAVQVRTN 395
            |||....:.::...|.  ..||     |.::..      .|:||||
Worm   410 LDTSSSESESSSPSNGGWSECD-----YKINGE------TVRVRTN 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532	16/88 (18%)
		PAN_1	236..327	CDD:394981	19/98 (19%)
		ZP	382..598	CDD:214579	5/14 (36%)
ZC449.1	NP_508855.1	PAN_AP	21..105	CDD:214680
		PAN_1	230..303	CDD:278453	15/75 (20%)
		PAN_1	317..391	CDD:278453	20/109 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158730
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030