DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cutl-26

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_741299.2	Gene:	cutl-26 / 176896	WormBaseID:	WBGene00021950	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	67/265 - (25%)
Similarity:	108/265 - (40%)	Gaps:	33/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 DVSVHCKDTRIAVQVRTNKPFNGRIYA-LGRSETCNIDVINSDAFRLDLTMAGQDCNTQ--SVTG 439
            ||...|.:..::|.:||:|||.|.:.. ...||.|.:....::...|.|.:...:|..:  ..:.
Worm    28 DVRWSCSEDVVSVFIRTSKPFEGLVQTRSSESEACRVQGFGTNVAVLKLNLKSDECGIKYDVASK 92

  Fly   440 VYSNTVVLQHHSVVMTKADKIYKVKCTYDMSSKNITFGMMPIRDPEMIHINS--SPEAPPPRIRI 502
            .||.||.:..|.|::.:.||...|.|      :.|..|..        |..|  :.::...::|:
Worm    93 TYSVTVDVHSHPVLIVEGDKSVNVTC------REIANGTQ--------HYASQMTSQSSDYQLRV 143

  Fly   503 LDTRQREVETVRIGDRLNFRIE-IP--EDTPYGIFARSCVAMAKDARTSFKIIDDDGCPTDPTIF 564
            |.:| ..|:||:.......:|. :|  :...|..|...|:|.......:.::.|..||....:|.
Worm   144 LSSR-LPVDTVKYSQPYTLQIRPLPSTQQNSYSFFVGQCIAQPVGGNVTVQLTDPVGCALFKSIM 207

  Fly   565 PGFTADGNALQSTYEA-----FRFTESYGVIFQCNVKYCLGPCEPAVCEWNMDSFESLGRRRRRS 624
            ..|.    ..:|..||     |||..:..:...|.|..|.|.||...|:.: .|..||..|...|
Worm   208 GHFA----RRESVEEAEIPSMFRFPNAKQLKISCIVTECDGSCEARTCDQD-SSASSLLERTTAS 267

  Fly   625 IESND 629
            .||.:
Worm   268 AESEE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	53/228 (23%)
cutl-26	NP_741299.2	Zona_pellucida	33..252	CDD:391783	57/237 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010