Protein Alignment tyn and cutl-28

DIOPT Version :9

• Sequence 1: NP_001027032.1
• Gene: tyn / 3354987
• FlyBaseID: FBgn0284435
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_499971.2
• Gene: cutl-28 / 176895
• WormBaseID: WBGene00018256
• Length: 696
• Species: Caenorhabditis elegans
• Alignment Length: 793
• Identity: 172/793 - (21%)
• Similarity: 282/793 - (35%)
• Gaps: 211/793 - (26%)

  Fly    17 PLLLCAVMVVLVTLPEQINARMAFEKLTDFDFPGNTYYSVKNL----------SLYECQGWCREE 71
            |.||   :::|.|||..::.       .:..|...|..||.:.          ||.:|..:|...
 Worm     4 PFLL---ILILSTLPSTVSP-------CEITFILETLKSVNSTASLIIRKSVDSLSQCTRFCSSV 58

  Fly    72 ADCQAAAFSFVVNPLSPSQETHCQLQNDSSAANPSAAPQRSANMYYMIKLQLRSENVC-HRPWSF 135
            .:|....||........:...:|.|.:.|.....|.:  |:......:      ||.| .|.::|
 Worm    59 PNCTHFTFSNAEPIEKKNGGFNCHLHSKSPVLTTSGS--RTVGTKTCL------ENKCLKRSFAF 115

  Fly   136 ERVPNKVIRGLDNALI---YTSTKEACLSACLNERRFVCRSVEYDYNNMKCVLSDSDRRS-SGQF 196
            |:.|.:.:  ::::.|   ::.:.|.|||.|..|..  ||:..::.:...|.||.....| ....
 Worm   116 EKFPGRSL--VNSSFIIKTFSISMEECLSQCQKESS--CRAALHNNDTSLCQLSRVSLNSVYNPR 176

  Fly   197 VQLVDAQGTDYFENLCLKPA---QACKNNRSFGNSQKMGVSEEKVAQYVGLHYYTDKELQVTSES 258
            :....:...|.:||.|:..|   .||...|..|...| .||::.: |.||            |..
 Worm   177 LYFKASYSVDLYENNCVDYAMTSSACTFMRVNGGGLK-SVSDQLI-QNVG------------SFD 227

  Fly   259 ACRLACEIESEF--LCRSFLYLGQPQGSQYNCRLYHLDHKTLPDGPSTYLNHERPLIDHGEPIGQ 321
            .|...|.|.|..  :|||:.|    ..|...|.|.....:.|...|   |...:|.:.||:
 Worm   228 ECEQMCVIRSRISDVCRSYTY----DNSTNECNLMWASARMLGRSP---LESMKPNLFHGD---- 281

  Fly   322 YFENQCEKAAGLGAGSPPGTLDKIDTLPVSLDTIEDPNLTNLTRNDVNCDKTGTCYDVSVHCKDT 386
                                             ::|                  |.:.|:.|::.
 Worm   282 ---------------------------------LDD------------------CVNFSLKCRED 295

  Fly   387 RIAVQVRTNKPFNGRIYA-LGRSETCNIDVINSDAF--RLDLTMAGQDCNTQSVTGVYSNTVVLQ 448
            .:.|:..:.:.|.|::.. ..:...|..|...:..|  :.|....|.|.| :|....|...|.::
 Worm   296 NLEVKASSMRMFIGKMMTKKSKKIMCQEDYEGNYDFSSKFDFKKCGLDPN-KSKDSTYRGMVHVK 359

  Fly   449 HHSV-VMTKADKIYKVKCTYDM---SSKNITFGMMPIRD--------PEMIHINSSPEAPPPR-- 499
            ..|. ::|..||:.:|.|....   |.:......|.:|:        .:::.:.:.|....|:
 Worm   360 EGSTSLVTIRDKVLQVNCRLHKSMPSEEQFLSVQMNVRENNKTNQVMSDVVVVTAPPAQTNPKFS 424

  Fly   500 IRILDTRQREVETVRIGD----RLNFRIEIPEDTPYGIFARSCVAMAKDARTS--FKIIDDDGC- 557
            ::||.....|.:||.|||    .|..:....:.|...:       :|||.:|.  .:|||:|||
 Worm   425 LKILGLDSTEADTVHIGDYGWIMLAVKNSAEDFTVTNL-------VAKDVQTGRVLRIIDEDGCV 482

  Fly   558 ----------PTDPTI-----FPGFTADGNALQSTYEAFRFTESYGVIFQCNVKYCLGPCEPAVC 607
                      .||..:     |.||.   ...:..|.|...|.:.|.:.:||....| |.|
 Worm   483 LRRDIVKEIRKTDNYVKLKISFSGFR---RQTEVVYHAMMETCTVGCMPKCNQDMML-PEE---- 539

  Fly   608 EWNMDSFE---SLGRRR--RRSIESNDTK---SEDDMNISQEILVLDFGDEKREFFKADPSTDFA 664
            |.|:.|..   .|.|.|  |||:.....:   :.|...::...|.|......::|....|.:||.
 Worm   540 ETNVHSLPLSLDLPRHRMVRRSLAGEPRELQLTSDVYKVTGHKLTLLNPPSPKQFDFPAPKSDFE 604

  Fly   665 -------KDKTVTIIEPCPTK-TSV---LALAVTCALMILLYISTLF----------CYYMKKWM 708
                   .:..|.:::..|.. |||   |...|||.|.::|....:|          ||| ::|.
 Worm   605 FNDNGEFHEGDVIVVKHSPNLWTSVKHCLIDDVTCMLTVVLGAIQMFLMFSCFLIMYCYY-QQWR 668

  Fly   709 --------QPHKI 713
                    |.|.:
 Worm   669 FYRELNRPQEHNV 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052	12/60 (20%)
		PAN_AP_HGF	131..210	CDD:238532	18/82 (22%)
		PAN_1	236..327	CDD:394981	21/92 (23%)
		ZP	382..598	CDD:214579	56/254 (22%)
cutl-28	NP_499971.2	APPLE	30..103	CDD:128519	14/74 (19%)
		PAN_1	114..192	CDD:278453	19/81 (23%)
		PAN_1	202..292	CDD:278453	30/165 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870