DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and cutl-15

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_495904.2	Gene:	cutl-15 / 174426	WormBaseID:	WBGene00011888	Length:	385	Species:	Caenorhabditis elegans

Alignment Length:	413	Identity:	76/413 - (18%)
Similarity:	147/413 - (35%)	Gaps:	107/413 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 EDPNLTNLTRNDVNCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNGRI-YALGRSETCNIDVINSD 419
            |:|.    .||:|..:.|       |.|....|.|::||...|.|.: ......:.|...::.::
Worm    25 EEPT----PRNEVLGEPT-------VSCAADAIYVKLRTKSTFLGHVDVKYSPDKACFQSLVTNN 78

  Fly   420 AFRLDLTMAGQDCNTQSVTGVYSNTVVLQ------HHSVVMTKADKIYKVKCTYDMSSKNITFGM 478
              ::::.:..::|.......::...|:|:      .|....|..|:|:.::| :.....|.|...
Worm    79 --QIEILIPHEECMVPRRRSLHPTGVILEVSLSVSFHPEFTTVDDRIFNMQC-FHQKKINGTSTS 140

  Fly   479 MPIRDPEMIHINSSPEAPPPRIRILDTRQREVETVRIGDRLNFRI-EIPEDTPYGIFA------- 535
            :.|..|:          |||.    ||:         |...::.: ..|...|.|..|
Worm   141 LAIGSPK----------PPPS----DTK---------GPSCSYEVLTSPGGLPAGRLALGQDVYH 182

  Fly   536 --------RSCVAMAK----DARTSFKIIDDDGCPTDPTIFPGFTADGNA-LQSTYEAFRFTESY 587
                    .||:.:..    ....:.::||..||....:|.|........ :.::.:.|..:.:.
Worm   183 SWQCQNVYESCIMIENCELVGGEETHEVIDSSGCSKHESIMPQLEYHNRTHVGTSVKVFGVSHTS 247

  Fly   588 GVIFQCNVK----YCLGPCEPAVCEWNMDSFESLGRRRRR---SIESNDTKSEDDMNISQEILVL 645
            .|.|.|.|:    ...|.|....|:        |.||:|.   ...|.|.:|: ::.|||.|.:.
Worm   248 IVYFACQVRLHPQLPTGECPKPKCD--------LMRRKREDSSQFPSIDVRSQ-NLEISQLINIT 303

  Fly   646 ------------------DFGDEKREFFKADPSTDFAKDKTVTIIEPCPTKTSVLALAVTCALMI 692
                              |...|.....:|..|....:::.      |....|||.:::...:.:
Worm   304 SSTMTPHPTEPPIQHTCPDIHVETESIEEASESKALDEERI------CADFRSVLVVSILLTVAL 362

  Fly   693 LLYISTLFCYYMKKWMQPHKIVA 715
            :|..:|:....:::  |.::|.:
Worm   363 ILITTTIVILIVRR--QKYEIAS 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	43/247 (17%)
cutl-15	NP_495904.2	ZP	41..272	CDD:214579	45/256 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910