DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and AgaP_AGAP005350

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	XP_315362.4	Gene:	AgaP_AGAP005350 / 1276057	VectorBaseID:	AGAP005350	Length:	398	Species:	Anopheles gambiae

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	108/277 - (38%)	Gaps:	68/277 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 NSDAFRLDLTMAGQDCNTQSVTGVYSNTVVLQHHSVVMTKAD---KIYKVKCTYDMSSKNITFGM 478
            |...|.|.||.. .||....|....:...|..|..:|.|..|   :|..|||.....|.|:|.|:
Mosquito    37 NLAVFELSLTNI-YDCGVTRVINQITGKKVFYHRIIVETGPDTGKEIVSVKCITTGPSYNVTHGI 100

  Fly   479 MP-------IRDPEMIHINSS--PEAPPPRIRILDTRQREVETVRIGDRL-----------NFRI 523
            :.       .::||.:.|.:|  ..||.|.:.|         .:|.||:|           :.::
Mosquito   101 VKRDVLPAGFQEPEDLEITTSITENAPEPSLGI---------AIRQGDKLVSGDLNVSPGAHLQM 156

  Fly   524 EIPEDTP----YGIFARSCVAMAKDARTSFKIIDDDGCPTDPTIFPGF-TADGNALQSTYEAFRF 583
            ||..|..    ||:...  ..:..|.:...:.|..:||..||.:|..| |.||:.|.:.:.||:|
Mosquito   157 EIFLDNRSAPIYGLGVN--YMLVTDTKYQEETIIFNGCSVDPYLFENFNTVDGDLLAAKFRAFKF 219

  Fly   584 TESYGVIFQCNVKYCLGPCEPAVCEWNMDSFESLGRRRRR----------------------SIE 626
            .||..|.|:..|..|:..|:..:|.....:|   |||:|.                      :.:
Mosquito   220 PESTYVQFRGTVNVCVDRCKGVICSNGQTAF---GRRKREISAAPADPNKVYEVTMTTFIKVNYD 281

  Fly   627 SN---DTKSEDDMNISQ 640
            .|   :|.||.|..|.|
Mosquito   282 ENADQNTVSEIDQKIRQ 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	58/208 (28%)
AgaP_AGAP005350	XP_315362.4	ZP	4..244	CDD:214579	60/218 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810