DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and AgaP_AGAP000786

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	XP_311326.5	Gene:	AgaP_AGAP000786 / 1272378	VectorBaseID:	AGAP000786	Length:	655	Species:	Anopheles gambiae

Alignment Length:	365	Identity:	76/365 - (20%)
Similarity:	130/365 - (35%)	Gaps:	109/365 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 IEDPN-LTNLTRNDVNCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNGRIYALGR-SETCNIDVIN 417
            :|.|: :.::|..:|.|.|             ..:.|.:..:.||.|.:.:.|: |:...|.|..
Mosquito    37 VERPDGMPSITALEVMCGK-------------DHMDVHLSFSAPFEGIVSSKGQHSDPRCIYVPP 88

  Fly   418 SD-----AFRLDLTMAG--QDCNTQSVTGVYSNTVVLQHHSVVMTKADKIYKVKCTYDMSSKNIT 475
            |.     .||:..:..|  .|.|.|    .|.||||:|:...::...|:..:::|.:
Mosquito    89 STGKTFFTFRISYSRCGTKPDLNGQ----FYENTVVVQYDKDLLEVWDEAKRLRCEW-------- 141

  Fly   476 FGMMPIRDPEMIHINSSPEAPPPRIRILDTRQREVETVRIGDRLNFRIEIPED-----------T 529
                 ..|.|     .:...||..|..||..|.:..    ||.::..:||.:.           .
Mosquito   142 -----FNDYE-----KTASKPPMVIADLDVIQLDFR----GDNVDCWMEIQQGKGPWAPAVSGIV 192

  Fly   530 PYG-----------------IFARSCVAMAKDARTSFKIIDDDGCPTDPTIFPGF----TADGNA 573
            |.|                 :..:|||| :..|....|:.|:.||...|.:...|    ..|..|
Mosquito   193 PLGSTMTLVVAINDFRGEFDMRVKSCVA-SDGAGHVIKLSDEYGCVLRPKMISRFLKARAPDDKA 256

  Fly   574 LQSTY---EAFRFTESYGVIFQCNVKYCLGPCEPAVCEWNMDSFESLG--------------RRR 621
            ...||   .||:|.::..|..:|.|:.|...|        :|..:..|              .::
Mosquito   257 SVITYAFFHAFKFPDALSVHIKCKVEICRHGC--------LDHCQHSGAPVGAGPAGVPGSAAKQ 313

  Fly   622 RRSIESNDT---KSEDDMNISQEILVLDFGDEKREFFKAD 658
            ...:|..||   ::.:|:.....:..||.|...::.:..|
Mosquito   314 HDLLERKDTLVNQNSNDILAGDSVEDLDSGMNGQDVYYDD 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	58/258 (22%)
AgaP_AGAP000786	XP_311326.5	ZP	53..284	CDD:214579	60/270 (22%)
AgaP_AGAP000786	XP_311326.5	Zona_pellucida	<192..285	CDD:278526	23/93 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X161
TreeFam	0	0.000	Not matched by this tool.
	2	1.910