DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tyn and LOC100491712

DIOPT Version :9

Sequence 1:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	XP_031760285.1	Gene:	LOC100491712 / 100491712	-ID:	-	Length:	953	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	90/458 - (19%)
Similarity:	148/458 - (32%)	Gaps:	135/458 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 LIYTSTKEACLSACLNERRFVCR---SVEY-DYNNMK----CVLSDSDRRSS---------GQFV 197
            |:....:..|.:| :|:..|:..   ||.| |::..|    .:.|..|...|         ..|.
Frog    24 LVNNDAQAGCRTA-VNDLVFIVDGSWSVRYKDFDTAKNWLLNITSSFDIGPSYTQVGVVQYSDFP 87

  Fly   198 QLVDAQG--TDYFENL-CLKPAQACKNNRS------------FGNSQKMGVSEEKVAQYVGLHYY 247
            ||....|  |.|.:.| .||..:....|.:            |..|:::.||:.|:|..:.....
Frog    88 QLEIPLGHNTSYQQLLSALKSIKYLGGNTNTGRAIKFATEEVFPTSKRLNVSKNKIAIVITDGKS 152

  Fly   248 TDKELQVTSESACR----LACEIESEFLCRSFLYLGQPQGSQYNCRLYHLDHKTLPDGPSTYLNH 308
            .|..:.::|.:..:    .|..:.||......:.:.....:.|  .||..|:.|:.....|....
Frog   153 QDNVVNISSSARAQGIILFAVGVGSEITKSELVAIANMPSTHY--VLYAEDYTTIDRIKETMRQK 215

  Fly   309 --ERPLIDHGEPIGQYFENQCEKAAGLGAGSPPGTLDKIDT----LPVSLDTIEDPNLTNLTRND 367
              |..:.....|:....|...|...|:          ||:|    :..||.:.|...||:
Frog   216 ICEESVCPTRIPVASRDEKGFELLVGM----------KINTKGQLVMGSLASEEAYLLTS----- 265

  Fly   368 VNCDKTGTCYDVSVH-CKDTRIAV-QVRTNKPFNGRIYALGR----------SETCN-------- 412
             |.|.|....|:... ...|.:.| .:|...|.|.:|..|.|          :.|.|
Frog   266 -NVDITENTRDIFPEGLPPTYVFVATIRLKSPGNNQIIDLWRIFSKAGEVQAAVTLNGINKSVLF 329

  Fly   413 -------------------IDVINSDAFRLDLTMAGQDCNTQSVTGVYSNTVVLQHHSVVMT--- 455
                               .||.:.|..:|.:.:..:      .|.:|.:...:|.|.:..|
Frog   330 TAVKINTDAQVVVFGDPRLKDVFSEDWHQLRIVVKNK------YTVLYLDDERIQSHPLEETGPI 388

  Fly   456 ------------KAD-----KIYKVK--CTYDMSSKNITFGMMPIRDP-------EMIHINSSPE 494
                        |.|     :|.|::  |..:.|.:.....:..:.||       :.|.|...||
Frog   389 FINGKTQVAKQWKTDETVTMEIQKLRLYCDPEQSERETACEIYSVDDPRCPLERKQPISICQCPE 453

  Fly   495 APP 497
            .||
Frog   454 GPP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532	19/78 (24%)
		PAN_1	236..327	CDD:394981	16/96 (17%)
		ZP	382..598	CDD:214579	33/184 (18%)
LOC100491712	XP_031760285.1	vWA_collagen	39..196	CDD:238749	31/158 (20%)
		LamG	251..419	CDD:419873	33/179 (18%)
		Collagen	502..558	CDD:396114
		Collagen	559..615	CDD:396114
		PHA03169	583..>778	CDD:223003
		Collagen	589..644	CDD:396114
		Collagen	820..874	CDD:396114
		Collagen	868..928	CDD:396114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910