Protein Alignment Set1 and ATX2

DIOPT Version :10

• Sequence 1: NP_001015221.1
• Gene: Set1 / 3354971
• FlyBaseID: FBgn0040022
• Length: 1641
• Species: Drosophila melanogaster
• Sequence 2: NP_172074.6
• Gene: ATX2 / 837093
• AraportID: AT1G05830
• Length: 1083
• Species: Arabidopsis thaliana
• Alignment Length: 1317
• Identity: 275/1317 - (20%)
• Similarity: 456/1317 - (34%)
• Gaps: 405/1317 - (30%)

  Fly   465 PEEIDNWD----EEEHDKNSIVPTHYGCMAKLQPPVPSNVNFA--------TKLQSVTQPNSDPG 517
            |:|.:..|    .|.||..:..|..|..:..:.....|:.:..        .|:.::..|.||..
plant     8 PKEEEGEDTQIKTELHDHAADNPVRYASLESVYSVSSSSSSLCCKTAAGSHKKVNALKLPMSDSF 72

  Fly   518 TVDLDTRIALIF-----KGKTFGNAPPFLQ---MDSSDSETDQGKPEVFSDVNSDSNNSENKKRS 574
            .:....|..::.     |.:.......||:   :.:...|.|....::.|....|....||||:.
plant    73 ELQPHRRPEIVHVYCRRKRRRRRRRESFLELAILQNEGVERDDRIVKIESAELDDEKEEENKKKK 137

  Fly   575 CEKNNKVLHQPNEASDISSDEELIGKKDKSKLSLICEKEVNDDNMSLSSLSSQEDPIQTKEGAEY 639
            .:|..                  ||..:..||.:        |:.:||  .|...|::   |...
plant   138 QKKRR------------------IGNGELMKLGV--------DSTTLS--VSATPPLR---GCRI 171

  Fly   640 KSIMSSYMYSHSNQNPFYYHASGYGHYLSGIPSESASRLFSNGAYVHSEYLKAVAS------FNF 698
            |::                        .||...:.:||...|......:.:.|.|:      .::
plant   172 KAV------------------------CSGNKQDGSSRSKRNTVKNQEKVVTASATAKKWVRLSY 212

  Fly   699 DSFSKPYDYNKGALSDQNDGIRQKV----------KQVIGYIVEELKQILKRDVNKRMIEITAFK 753
            |.....:..          |::.||          ..::||.||....|:|
plant   213 DGVDPKHFI----------GLQCKVFWPLDAVWYPGSIVGYNVETKHHIVK-------------- 253

  Fly   754 HFETWWD---EHTSKARSKPLFEKADSTVNTPLNCIKDTSYNEKNPDINLLINAHREVADFQSYS 815
                :.|   |..:..|.|                ||.....:....:|:....:..|.|.|.|.
plant   254 ----YGDGDGEELALRREK----------------IKFLISRDDMELLNMKFGTNDVVVDGQDYD 298

  Fly   816 SIGLRAAMPKLPSFRRIRKHPSPIPTKRNFLERD---------------LSDQEEMVQRSDSDKE 865
            .:.:.||     ||...          ::|..||               :.|:..:|:|...:.:
plant   299 ELVILAA-----SFEEC----------QDFEPRDIIWAKLTGHAMWPAIIVDESVIVKRKGLNNK 348

  Fly   866 DSN-----VEI---SDTARSKIKGPVPIQESDSKSHTSGLNSKR--KGSASSFFSSSSSSTSSEA 920
            .|.     |:.   .|.||.::|..|        |...||.|:.  |.....|..:...:.....
plant   349 ISGGRSVLVQFFGTHDFARIQVKQAV--------SFLKGLLSRSPLKCKQPRFEEAMEEAKMYLK 405

  Fly   921 EYEA------------IDCVEKARTSEEDSPRGYGQRNLNQRTTTIRNRNL------VGTMDVIN 967
            ||:.            .||.|:..:.||||... |..........:|...|      :|.:.:||
plant   406 EYKLPGRMDQLQKVADTDCSERINSGEEDSSNS-GDDYTKDGEVWLRPTELGDCLHRIGDLQIIN 469

  Fly   968 VRNLCSGSNEFKKENVTKRTKKNIYSDTDEDNDRTLFPALKEKNIST-----ILSDLE------- 1020
            :..:.:.|..||.   :|.|....|:.|.:      |.:||:.|.|.     :|.|.|
plant   470 LGRIVTDSEFFKD---SKHTWPEGYTATRK------FISLKDPNASAMYKMEVLRDAESKTRPVF 525

  Fly  1021 EISKDSCIGLDENGIEPTI--------LRKI----PNTPKLNEECRRSLTPVPPPGYNEEEIKKK 1073
            .::.:|  |....|..|:.        ::||    .|...|.|....|.|.:  .|::..|:.|.
plant   526 RVTTNS--GEQFKGDTPSACWNKIYNRIKKIQIASDNPDVLGEGLHESGTDM--FGFSNPEVDKL 586

  Fly  1074 VD---CKQKPSFEYDRIYSDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIE-KSLDK----- 1129
            :.   ..:.||....|.||..    :||:   ..|.|           :..|:| |.|||
plant   587 IQGLLQSRPPSKVSQRKYSSG----KYQD---HPTGY-----------RPVRVEWKDLDKCNVCH 633

  Fly  1130 -NLQSPNNIVKNNNSPRNKNDETRKTAISQTRSCFESASKVDTTLVNIISVENDINEFGPHEEGD 1193
             :.:..||:....:..|         .:..|| |:                    .:..||....
plant   634 MDEEYENNLFLQCDKCR---------MMVHTR-CY--------------------GQLEPHNGIL 668

  Fly  1194 VLTNGCNKMYTNSKGKTKRTQSPVYSEGGSSQASQASQVALEHCYSLPPHSVSLGDYPSGKVNET 1258
            .|.|.|..:..:...:.  ...||.  ||:.:.:...:.|...|....|.:..|.......::..
plant   669 WLCNLCRPVALDIPPRC--CLCPVV--GGAMKPTTDGRWAHLACAIWIPETCLLDVKKMEPIDGV 729

  Fly  1259 KNILKREAENIAIVSQMTRTGPGRPRKDPICIQKKK-------RDLAPRMSNVKSKMTPNGDEWP 1316
            |.:.|...:.:..:..::...         |||...       ..|..|.:.:          ..
plant   730 KKVSKDRWKLLCSICGVSYGA---------CIQCSNNTCRVAYHPLCARAAGL----------CV 775

  Fly  1317 DLAHKNVHFVPCDMYKTRDQNEEMVILYTFLTKGIDAEDINFIKMSYLDHLHKEPYAMFLNNTHW 1381
            :||.::..|:   :....|:.::.:.|.:|..:                  |::.....|...:.
plant   776 ELADEDRLFL---LSMDDDEADQCIRLLSFCKR------------------HRQTSNYHLETEYM 819

  Fly  1382 VDHCTTDRAFWPPPSKKRRKDDELIRHKTGCARTEGFYKLDVREKAKHKYHYAKANTEDSFNEDR 1446
            :........:.|||            :.:||||||.:..|..|.:
plant   820 IKPAHNIAEYLPPP------------NPSGCARTEPYNYLGRRGR-------------------- 852

  Fly  1447 SDEPTALTNHHHNKLISKMQ-----GISREARSNQRRLLTAFGS-----------MGESELLKFN 1495
             .||.||......:|..:.|     |.||...|...|:   :||           :..:|...|.
plant   853 -KEPEALAGASSKRLFVENQPYIVGGYSRHEFSTYERI---YGSKMSQITTPSNILSMAEKYTFM 913

  Fly  1496 QLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRE-TKYEAIGIGSSYLF 1559
            :..:||: |.|.||.||.:|:||..|..|.:|||||.|:::||.:||.|| ..|.::....:|:|
plant   914 KETYRKR-LAFGKSGIHGFGIFAKLPHRAGDMVIEYTGELVRPPIADKREHLIYNSMVGAGTYMF 977

  Fly  1560 RIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQPIGINEEITYDYKFPLED 1624
            |||.|.:||||:.|::|..|||||.||||::||::..::.|:|::|:.:...||:||||:|...|
plant   978 RIDNERVIDATRTGSIAHLINHSCEPNCYSRVISVNGDEHIIIFAKRDVAKWEELTYDYRFFSID 1042

  Fly  1625 EKIPCLCGAQGCRGTLN 1641
            |::.|.||...|||.:|
plant  1043 ERLACYCGFPRCRGVVN 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set1	NP_001015221.1	RRM_Set1	99..191	CDD:409745
		U2AF_lg	255..>386	CDD:273727
		N-SET	1352..1496	CDD:463344	28/159 (18%)
		SET_SETD1	1490..1637	CDD:380946	66/147 (45%)
ATX2	NP_172074.6	Tudor_Agenet_AtEML-like	221..271	CDD:410475	14/93 (15%)
		PWWP_AtATX1-like	314..410	CDD:438970	20/103 (19%)
		FYRN	463..513	CDD:461787	15/58 (26%)
		FYRC	524..610	CDD:197781	19/93 (20%)
		PHD_ATX1_2_like	628..674	CDD:276969	11/75 (15%)
		ePHD_ATX1_2_like	685..806	CDD:277132	21/164 (13%)
		SET_SETD1-like	906..1055	CDD:380916	66/149 (44%)