Protein Alignment Set1 and SDG14

DIOPT Version :10

• Sequence 1: NP_001015221.1
• Gene: Set1 / 3354971
• FlyBaseID: FBgn0040022
• Length: 1641
• Species: Drosophila melanogaster
• Sequence 2: NP_191733.3
• Gene: SDG14 / 825347
• AraportID: AT3G61740
• Length: 1018
• Species: Arabidopsis thaliana
• Alignment Length: 1259
• Identity: 249/1259 - (19%)
• Similarity: 412/1259 - (32%)
• Gaps: 399/1259 - (31%)

  Fly   533 TFGNAPPFLQMDSSDSETDQGK-----------------------PEVFSDVNSDSNNSENKKRS 574
            ||.|..  |:....|||.:.|:                       ||:.:..:|...:.|..::.
plant     9 TFENQN--LKRCKIDSEIEYGRKKGEIIVYKKRQRATVDQPCSKEPELLTSSSSSLTSKEESQQV 71

  Fly   575 CEKNNKVLHQPNEASDISSDEELIGK-KDKSKLSLICEKEVNDDNMSLSSLSSQEDPIQTKEGAE 638
            |...:|.......|......:.::|. |...:.....|...:||::||              |.:
plant    72 CSDQSKSSRGRVRAVPSRFKDSIVGTWKSSRRKGESTESSHDDDDVSL--------------GKK 122

  Fly   639 YKSIMSSYMYSHSNQNPFYYHASGYGHYLSGIPSESASRLFSNGAYVHSEYLKAVASFNFDSFSK 703
            .|....|.....|..:..:....      :|..||           |..:|.....|::..:|..
plant   123 VKGFSGSSKLHRSKDSKVFPRKD------NGDSSE-----------VDCDYWDVQISYDDANFGM 170

  Fly   704 PYDYNKGALSDQNDGIRQKVKQVIGYIVEELKQILKRDVNKRMIEITAFKHFETWWDEHTSKARS 768
            |         .::|..|:.|.:...:.|.:|            :.....|.|..|     .....
plant   171 P---------KKSDASRKGVYKPEEFTVGDL------------VWAKCGKRFPAW-----PAVVI 209

  Fly   769 KPLFEKADSTVNTPLNCIKDTSYNEKNPDINLLINAHREVADFQSYSSIGLRAAMPKLPSFRRIR 833
            .|:.:..|..:.   :|:...        |.::...:.:....:.|:.:......|......:.:
plant   210 DPISQAPDGVLK---HCVPGA--------ICVMFFGYSKDGTQRDYAWVRQGMVYPFTEFMDKFQ 263

  Fly   834 KHPSPIPTKRNFLERDLSDQEEMVQRSDSDKEDSNVEISDTARSKIKGPVPIQESDSKSHTSGLN 898
            ...:....|.:...:.|   ||.|...:.:..|:.:...|::.:         |||
plant   264 DQTNLFNYKASEFNKAL---EEAVLAENGNFGDAEIISPDSSAT---------ESD--------- 307

  Fly   899 SKRKGSASSFFSSSSSSTSSEAEYEAIDCVEKARTSEEDSPRGYGQRNLNQRTTTIRNRNLVGTM 963
             :..|.||.|          :..|.     |..||.:     |.|        :.:..::|..|.
plant   308 -QDYGPASRF----------QGSYH-----EDIRTCD-----GCG--------SVMPLKSLKRTK 343

  Fly   964 DVINVRNLCSGSNEFKKENVTKRTKKNIYSDTDE--------------------DNDRTLFPALK 1008
            |......||...::.:|.|......|.|:..:|:                    .|:|  |..|:
plant   344 DSQPEELLCKHCSKLRKSNQYCGICKRIWHPSDDGDWVCCDGCDVWVHAECDNITNER--FKELE 406

  Fly  1009 EKN------------ISTILSDLEEI----SKDSCIGLDE------NGIEPTILRKIPNTPKLNE 1051
            ..|            ..|||.:...:    .|.:..||.:      ||:|.|.:||....
plant   407 HNNYYCPDCKVQHELTPTILEEQNSVFKSTEKTTETGLPDAITVVCNGMEGTYIRKFHAI----- 466

  Fly  1052 ECRRSLTPVPPPGYNEEEIKKKVDC---KQKPSFEYDRIYSDSEEEKEYQERRKRNTEYMAQMER 1113
            ||                  |...|   ||.|| |::|......::.:|..|.|   :.|..:|:
plant   467 EC------------------KCGSCGSRKQSPS-EWERHTGCRAKKWKYSVRVK---DTMLPLEK 509

  Fly  1114 EFLEEQEKRIE-KSLDKNLQSPNNIVKNNNSPRNKNDETRKTAISQTRSCFESASKVDTTLVNII 1177
            ...|.....:| :.|||  |...::::....|......|.:.|:.:....:|....:   :.|..
plant   510 WIAEFSTYTLETQMLDK--QKMLSLLEEKYEPVRAKWTTERCAVCRWVEDWEENKMI---ICNRC 569

  Fly  1178 SVENDINEFGPHEEGDVLTNGCNKMYTNSKGKTKRTQSPVYSEGGSSQASQAS------------ 1230
            .|......:|..:..|:.:..|....|..   .:|.......:||:.:.|...
plant   570 QVAVHQECYGVSKSQDLTSWVCRACETPD---IERDCCLCPVKGGALKPSDVEGLWVHVTCAWFR 631

  Fly  1231 -QVALEHCYSLPPHSVSLGDYPSGKVNETKNILK----------------------REAENIAIV 1272
             :|...:..::.| :|.|...|:....:...|.|                      |...|:.:
plant   632 PEVGFLNHENMEP-AVGLFKIPANSFLKVCTICKQTHGSCVHCCKCATHFHAMCASRAGYNMEL- 694

  Fly  1273 SQMTRTGPGRPRKDPICIQKKKRDLAPRMSNVKSKMTPNGDEWPDLAHKNVHFVPCDMYKTRDQN 1337
            ..:.:.|..|.||...|...:|.|                   ||
plant   695 HCLEKNGVQRTRKSVYCSFHRKPD-------------------PD-------------------- 720

  Fly  1338 EEMVILYTFLTKGIDAEDINFIKMSYLDHLHKEPYAMF-----LNNTHWVDHCTTDRAFWPPPSK 1397
             .:|:::|                         |..:|     |.|.:
plant   721 -SVVVVHT-------------------------PSGVFGSRNLLQNQY----------------- 742

  Fly  1398 KRRKDDELIRHKTGCARTEGFYKLDVREK--------AKHKYHYAKANTEDSFN--EDRSDEPTA 1452
            .|.|...|:..|.  .:..||......|:        |.....|:::||:....  ..|...|
plant   743 GRAKGSRLVLTKK--MKLPGFQTQTQAEQSRVFDSLSAARCRIYSRSNTKIDLEAISHRLKGP-- 803

  Fly  1453 LTNHHHNKLISKMQGISREARSNQRRLLTAFGSMGE--SELLK---------------FNQLKFR 1500
              :||....|..:... :.:.|.:...::.|..:|.  ||.|:               |...:.|
plant   804 --SHHSLSAIENLNSF-KASFSFRAPFMSVFCFLGATFSEYLRKILISIYLVTHQEADFTSFRER 865

  Fly  1501 KKQLK--------FAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRETKYEAIGIGSSY 1557
            .|.|:        |.||.||.|||||.:.|...||:|||.|..:|..||||||..|.:.| ...|
plant   866 LKHLQRTENFRVCFGKSGIHGWGLFARKSIQEGEMIIEYRGVKVRRSVADLREANYRSQG-KDCY 929

  Fly  1558 LFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITI--ESEKKIVIYSKQPIGINEEITYDYKF 1620
            ||:|..|.:||||..||:||.|||||.|||||:::::  ..:.:||:.:|..:...||:||||.|
plant   930 LFKISEEIVIDATDSGNIARLINHSCMPNCYARIVSMGDGEDNRIVLIAKTNVAAGEELTYDYLF 994

  Fly  1621 PL---EDEKIPCLCGAQGCRGTLN 1641
            .:   |:.|:||||.|..||..:|
plant   995 EVDESEEIKVPCLCKAPNCRKFMN 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set1	NP_001015221.1	RRM_Set1	99..191	CDD:409745
		U2AF_lg	255..>386	CDD:273727
		N-SET	1352..1496	CDD:463344	27/175 (15%)
		SET_SETD1	1490..1637	CDD:380946	72/174 (41%)
SDG14	NP_191733.3	PWWP_AtATX3-like	188..292	CDD:438971	16/134 (12%)
		PHD_TCF19_like	365..415	CDD:276992	8/51 (16%)
		COG5141	<518..>765	CDD:227470	49/340 (14%)
		ePHD_ATX3_4_5_like	603..714	CDD:277133	17/112 (15%)
		SET_SETD1-like	862..1014	CDD:380916	69/152 (45%)