Protein Alignment Set1 and CLF

DIOPT Version :10

• Sequence 1: NP_001015221.1
• Gene: Set1 / 3354971
• FlyBaseID: FBgn0040022
• Length: 1641
• Species: Drosophila melanogaster
• Sequence 2: NP_179919.1
• Gene: CLF / 816870
• AraportID: AT2G23380
• Length: 902
• Species: Arabidopsis thaliana
• Alignment Length: 1139
• Identity: 203/1139 - (17%)
• Similarity: 365/1139 - (32%)
• Gaps: 452/1139 - (39%)

  Fly   671 PSESASRLFSNGAYVHSEYLKAVASFNFDSFSKPYDYNKGALSDQNDGIRQKVKQVIGYIVEELK 735
            ||.||:|                        |:|   .|.:.:::.....::|.:||    |.||
plant     7 PSSSATR------------------------SEP---PKDSPAEERGPASKEVSEVI----ESLK 40

  Fly   736 QILKRD----VNKRMIEITAFKHFETWWDEHTSKARSKPLFEKADSTVNTPL----NCIKDTSYN 792
            :.|..|    :.||:             ||:     .|.||....|.:.:.:    :| ||.|
plant    41 KKLAADRCISIKKRI-------------DEN-----KKNLFAITQSFMRSSMERGGSC-KDGS-- 84

  Fly   793 EKNPDINLLI----------------NAHREVADFQSYSSIGLRAAMP--------KLPSFRRIR 833
                  :||:                |.:|.|.|..:.|.:...:::|        |:|..:|:.
plant    85 ------DLLVKRQRDSPGMKSGIDESNNNRYVEDGPASSGMVQGSSVPVKISLRPIKMPDIKRLS 143

  Fly   834 KHPSPIPTKRNFLERDLSDQEEMVQR--------------SDSDKE--DSNVEISDTARSKIKGP 882
            .:.:.:...||  :|...||..:.:|              |||::|  |...|..|.
plant   144 PYTTWVFLDRN--QRMTEDQSVVGRRRIYYDQTGGEALICSDSEEEAIDDEEEKRDF-------- 198

  Fly   883 VPIQESD----SKSHTSGLNSKRKGSASSFFSSSSSSTSSEAEYEAIDCVEKARTSEEDSPRGYG 943
              ::..|    ......||:.......:||.|.|:|..             |||.......:...
plant   199 --LEPEDYIIRMTLEQLGLSDSVLAELASFLSRSTSEI-------------KARHGVLMKEKEVS 248

  Fly   944 QRNLNQRTTTIRNRNLVGTMD-----------VINVR------------------------NLCS 973
            :...||..:::.|:::.|.:|           |.:.|                        ||..
plant   249 ESGDNQAESSLLNKDMEGALDSFDNLFCRRCLVFDCRLHGCSQDLIFPAEKPAPWCPPVDENLTC 313

  Fly   974 GSNEFK----------------KENV------TKRTKKNIYSDTDEDNDRTLFPALKEKNISTIL 1016
            |:|.:|                |...      ||.|.....|..:....:| ||:  |...|...
plant   314 GANCYKTLLKSGRFPGYGTIEGKTGTSSDGAGTKTTPTKFSSKLNGRKPKT-FPS--ESASSNEK 375

  Fly  1017 SDLEEISKDSCIGLDENGI-EPTILRKIPNTPKLNEECRRSLTPVPPPGYNEEEIKKKVDCKQKP 1080
            ..||  :.||     |||: :.|...|:.::||:....||
plant   376 CALE--TSDS-----ENGLQQDTNSDKVSSSPKVKGSGRR------------------------- 408

  Fly  1081 SFEYDRIYSDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIEKSLDKNLQSPNNIVKNNNSPR 1145
                              ..||||...:|:......::::|:.|.|      ..::|...:.||.
plant   409 ------------------VGRKRNKNRVAERVPRKTQKRQKKTEAS------DSDSIASGSCSPS 449

  Fly  1146 NKNDETRKTAISQTRSCFESAS------------------KVDTTLVNIISVENDINEFGPHEE- 1191
            :...:..:.|.|.::...:|.:                  |.|..:.....|.::::..|..|.
plant   450 DAKHKDNEDATSSSQKHVKSGNSGKSRKNGTPAEVSNNSVKDDVPVCQSNEVASELDAPGSDESL 514

  Fly  1192 ------GDVLTNG---CNKMYTNSKGKTKRTQSPVYSEGGSSQASQASQVA------LEHCYSLP 1241
                  |:.::.|   .||::       :..:..::.:|.......:..:|      .:.|:.:.
plant   515 RKEEFMGETVSRGRLATNKLW-------RPLEKSLFDKGVEIFGMNSCLIARNLLSGFKSCWEVF 572

  Fly  1242 PHSV------------SLGDYPSGKVNETKNILKREAENIAIVSQMTRTGPGRPRKDPICIQKKK 1294
            .:..            .|....|.|.:...|::..:                        ::::.
plant   573 QYMTCSENKASFFGGDGLNPDGSSKFDINGNMVNNQ------------------------VRRRS 613

  Fly  1295 RDLAPRMSNVKSKMTPNGDEWPDLAHKNV-------------HFVPCDMYKTRDQNEEMVILYTF 1346
            |.|..|....:.|.|     |...|:.::             .|.||:
plant   614 RFLRRRGKVRRLKYT-----WKSAAYHSIRKRITEKKDQPCRQFNPCN----------------- 656

  Fly  1347 LTKGIDAEDINFIKMSYLDHLHKEPYAMFLNNTHWVDHCTTDRAFWPPPSKKRRKDDELIRHKTG 1411
                        .|::    ..|| ....||.|....:|                         |
plant   657 ------------CKIA----CGKE-CPCLLNGTCCEKYC-------------------------G 679

  Fly  1412 CARTEGFYKLDVREKAKHKY---HYAKANTED----SFNEDRSDEPTALTN-----HHHNKLISK 1464
            |.::           .|:::   |.||:....    .|..||..:|....|     ...:..:..
plant   680 CPKS-----------CKNRFRGCHCAKSQCRSRQCPCFAADRECDPDVCRNCWVIGGDGSLGVPS 733

  Fly  1465 MQGISREARSNQRRLLTAFGSMGESELLKFNQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVI 1529
            .:|.:.|.| |.:.||.                  :::::....|.:..||.|....::..|.:.
plant   734 QRGDNYECR-NMKLLLK------------------QQQRVLLGISDVSGWGAFLKNSVSKHEYLG 779

  Fly  1530 EYVGQMIRPVVADLRETKYEAIGIGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITI 1594
            ||.|::|....||.|...|:.  ...|:||.::.:.::||.:.|:..:|.|||..||||||||.:
plant   780 EYTGELISHKEADKRGKIYDR--ENCSFLFNLNDQFVLDAYRKGDKLKFANHSPEPNCYAKVIMV 842

  Fly  1595 ESEKKIVIYSKQPIGINEEITYDYKFPLEDEKIP 1628
            ..:.::.|::|:.|...||:.|||::  |.::.|
plant   843 AGDHRVGIFAKERILAGEELFYDYRY--EPDRAP 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set1	NP_001015221.1	RRM_Set1	99..191	CDD:409745
		U2AF_lg	255..>386	CDD:273727
		N-SET	1352..1496	CDD:463344	24/155 (15%)
		SET_SETD1	1490..1637	CDD:380946	41/139 (29%)
CLF	NP_179919.1	preSET_CXC	690..721	CDD:408079	8/30 (27%)
		SET_EZH	752..868	CDD:380917	39/117 (33%)