Protein Alignment Set1 and Su(var)3-9

DIOPT Version :10

• Sequence 1: NP_001015221.1
• Gene: Set1 / 3354971
• FlyBaseID: FBgn0040022
• Length: 1641
• Species: Drosophila melanogaster
• Sequence 2: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 153/729 - (20%)
• Similarity: 269/729 - (36%)
• Gaps: 203/729 - (27%)

  Fly  1007 LKEKNISTI----LSDL--EEISKDSCIGLDENGI----EPTILRKIP--NTPKLNEECRRSLTP 1059
            |:::::|.:    |:.|  |.||:.:.|.:...|.    :.|:::.|.  .|.:...|..|::|
  Fly    14 LQKQDLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT- 77

  Fly  1060 VPPPGYNEEEIKKKVDCKQKPSFEYDRIYSDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIE 1124
            :.....:|::||..:..||              :.::|:.:::....::|::.|      ..|..
  Fly    78 IKLERLSEKKIKNLLTSKQ--------------QRQQYEIKQRSMLRHLAELRR------HSRFR 122

  Fly  1125 KSLDKNLQSPNNIVKNNNSPRNKNDETRKTAISQTRSC-FESASKVDTTLVNIISVENDINEFGP 1188
            :...|...|......::...|.....|.:|::|.:.|. :.|.                   ||
  Fly   123 RLCTKPASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSV-------------------FG- 167

  Fly  1189 HEEGDVLTNGCNKMYT-NSKGKTKRTQSPVYSEGGSSQASQASQVALEHCYSLPPHSVSLGDYPS 1252
            .||.||     :|:.: |...|.||.:|...  |..:..|:.|:..:......||.    |:|..
  Fly   168 CEEHDV-----DKIPSLNGFAKLKRRRSSCV--GAPTPNSKRSKNNMGVIAKRPPK----GEYVV 221

  Fly  1253 GKV-------------------NETKNILKREAENIAIVSQMTRTGPGRPRKDPICIQK------ 1292
            .::                   ::::|..:..| |:|..::|.:......:...|.|.|
  Fly   222 ERIECVEMDQYQPVFFVKWLGYHDSENTWESLA-NVADCAEMEKFVERHQQLYEIYIAKITTELE 285

  Fly  1293 KKRDLAPRMSNVKSKMTPNGDEWPDLAHKNVHFVPCDMYK---TRDQNEEMVILYTFLTKGIDAE 1354
            |:.:..|.|.|:   .....|.:..| :..:..:....|:   :|.|.|...|....| |.:..:
  Fly   286 KQLEALPLMENI---TVAEVDAYEPL-NLQIDLILLAQYRAAGSRSQREPQKIGERAL-KSMQIK 345

  Fly  1355 DINFIKMSYL----------DHLHK-EPYAMFLNNTHWVDHCTTDRAFW-----------PPPSK 1397
            ...|::...|          :|:.| .|.....||   :|..|.|..|.           |.|..
  Fly   346 RAQFVRRKQLADLALFEKRMNHVEKPSPPIRVENN---IDLDTIDSNFMYIHDNIIGKDVPKPEA 407

  Fly  1398 -----KRRKDDELIRHKTG-CARTEGFYKLDVREKAKHKYHYAKANTEDSFNEDRSDEPTALTNH 1456
                 |..:|.|.....|. |||..|  :|...|::..:......:.....|...|.:.:.
  Fly   408 GIVGCKCTEDTEECTASTKCCARFAG--ELFAYERSTRRLRLRPGSAIYECNSRCSCDSSC---- 466

  Fly  1457 HHNKLISKMQGISREARSNQRRLL---TAFGSMGESELLKFNQLKFRKKQLKFAKSAIHDWGLFA 1518
             .|:|:.         ...|..|:   ||.||                           .||:.|
  Fly   467 -SNRLVQ---------HGRQVPLVLFKTANGS---------------------------GWGVRA 494

  Fly  1519 MEPIAADEMVIEYVGQMIRPVVADLRETKYEAIGIGSSYLFRIDMET------IIDATKCGNLAR 1577
            ...:...|.|.||:|::|....|:.|...|:  ..|.:|||.:|..|      .|||...||::.
  Fly   495 ATALRKGEFVCEYIGEIITSDEANERGKAYD--DNGRTYLFDLDYNTAQDSEYTIDAANYGNISH 557

  Fly  1578 FINHSCNPN-----CYAKVITIESEKKIVIYSKQPIGINEEITYDYKFPLEDEKIP--------- 1628
            ||||||:||     |:.:.:.: :...:|.::.:||...||:::|| ...::|.:|
  Fly   558 FINHSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGEELSFDY-IRADNEDVPYENLSTAVR 620

  Fly  1629 --CLCGAQGCRGTL 1640
              |.|||..||..|
  Fly   621 VECRCGADNCRKVL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set1	NP_001015221.1	RRM_Set1	99..191	CDD:409745
		U2AF_lg	255..>386	CDD:273727
		N-SET	1352..1496	CDD:463344	33/174 (19%)
		SET_SETD1	1490..1637	CDD:380946	45/168 (27%)
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	15/66 (23%)
		Chromo	219..268	CDD:459793	6/49 (12%)
		SET_SUV39H	388..634	CDD:380940	70/292 (24%)