|
Fly 15 NSHDSSLANSKMP--------------RNFKLLSDPQLVKCGTRLYRYDG---LMPGDPSYPTIT 62
|||.....:.:.| |::||:.||.|.|...:|||||| .:....:.|...
Human 3 NSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMSSNRPVEI 67
Fly 63 PRDPRNPLIRIRARAVEPLMLLIPRFVIDSDYVGQPPAVEVTIVNLNDNIDKQFLASMLDKCGTS 127
..||| ::.|..:..| |.|.:|:|.||..|||..|..:||...|||||.:.||..|..|.|..
Human 68 VEDPR--VVGIWTKNKE-LELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEV 129
Fly 128 DEINIYHHPITNKHLGIARIVFDSTKGARQFVEKYNQKSVMGKILDVFCDPFGATLKKSLESLTN 192
:|:.|.::|.|.||||||::||.:.:||:..|:..:..||||.|:.|..|..|.|..:..|.|
Human 130 EEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDTKGETRMRFYELL-- 192
Fly 193 SVAGKQLIGPKVTPQWTFQQAALEDTEFIHGYPEKNGEHIKDIYTTQTNHEIPNRSRDRNWNRDK 257
|.| :.||| |.....|:....|.....:..:.:|.:
Human 193 -VTG------RYTPQ-TLPVGELDAVSPIVNETLQLSDALKRL---------------------- 227
Fly 258 ERERDRHFKERSRHSSERSYDRDRGMRENVGTSIRRRRTFYRRRSSDISPED-----SRDILIMT 317
:|.|:....|:. ||.::|.. |:|....:
Human 228 ---------------------KDGGLSAGCGSG-----------SSSVTPNSGGTPFSQDTAYSS 260
Fly 318 RERSRDSDSRPRDYCRSRERESFRDRKRSHEKGRD-QPREKREHYYNSSKDREYRGR-------- 373
|| .|...|:.:|.. .||..... |:|..|..|
Human 261 --------------CR-------LDTPNSYGQGTPLTPRLGTPF----SQDSSYSSRQPTPSYLF 300
Fly 374 DRDRSAEIDQRDRGSLKYCSRYSL---HEYIETD--VRRSSNTISSYYSASSLPI-ASHGFNSCS 432
.:|.:.....| |...|:...|:. |.|:... |...:...:::..:|.||. |..|....|
Human 301 SQDPAVTFKAR-RHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSS 364
Fly 433 FPSIENIKTWSDRRAWT----------AFQPDFHPVQPP----PPPPEEIDNWDEEEHDKNSIVP 483
.|..:.....|...|.| .|:..|.|.|.| |||||| |
Human 365 GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEE---------------P 414
Fly 484 T---HYGC-------MAKLQPPVPSNVNFATKLQSVTQPNSDPGTVDLDTRIALIFKGKTFGNAP 538
| .:|. .|...||:|.....|.: :|.:.||....||....:....|||.:|
Human 415 TATAAFGARDSGEFRRAPAPPPLPPAEPLAKE-----KPGTPPGPPPPDTNSMELGGRPTFGWSP 474
Fly 539 --------------------PFLQMDS------------------SDSETD---QGKPEVFSDVN 562
|...:|| .||:|: :|.| ::
Human 475 EPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP-----IS 534
Fly 563 SDSN----------NSENKKR-----SCEKNNKVLH--QPNEASDISSDEE-------------- 596
|.|: ||:...| |...::..|. .|....|...|||
Human 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG 599
Fly 597 -----------------LIG-------KKDKSKLSLICEKEVNDDNMSLSSLSSQE--DPIQTKE 635
|:| |.|:.:.|...:.|::||.|..:.::|.: .|:....
Human 600 PPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP 664
Fly 636 GAEYKSIMSSYMYSHSNQNP--------------------------------------------- 655
|| .::.:..:.:.:...|
Human 665 GA--AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP 727
Fly 656 -------------------------FYYHASGYGHYLSG----------IPSESASRLFS-NGAY 684
|........|.|.| :.::..|||.: .||.
Human 728 PPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGAC 792
Fly 685 VHSEYLKAVAS--------FNFDSFSKPYDYNK----------------------GALSDQNDGI 719
.:..::.|.|: .|...:..|:..:. |.:..|.|..
Human 793 PYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPH 857
Fly 720 RQKVKQVIGYIVEELKQILKRDVNKRMIEITAFKHFETWWD----------------EHTSKARS 768
:..|..|:..:::|||.|:|||:|::|:|:.||:.|:.||| ||..:.|.
Human 858 KATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDEDRP 922
Fly 769 KPLFEKADSTVNTPLNCIKDTSYNEKNPDINLLINAHREVADFQSYS-SIGLRAAMPKLPSFRRI 832
||....| :|:.: |:.: .|...::... .||||.|: :||||:..
Human 923 KPKDRIA--------SCLLE-SWGK------------GEGLGYEGLGLGIGLRGAI-RLPSFKVK 965
Fly 833 RKHPSPIPTKRNFLER-------DLSDQEEMVQRSDSDKEDSNVEISDTARSKIKG--------- 881
||.| |..|.....:| |..|:|...:| |.|..|:..|: |:...||
Human 966 RKEP-PDTTSSGDQKRLRPSTSVDEEDEESERER-DRDMADTPCEL---AKRDPKGVGVRRRPAR 1025
Fly 882 PVPIQESDSKSHTSGLNSKRKGSASSFFSSSSSSTSS-----EAEYEAIDCVEKARTSEEDS-PR 940
|:.:.....:.....|::....||||...||::|.|| |.|.|:.:..|:|...||:. ||
Human 1026 PLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEQESTEEEEEAEEEEEEEVPR 1090
Fly 941 GYGQRNLNQRTTTIR-----------NRNLVGTMDVINVRNLCSGSNE---FKKENVTKRTKKNI 991
. .|:..:|:.. :|:.....|.....:..|..:| .::|.|:..|.|..
Human 1091 S----QLSSSSTSSTSDKDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE 1151
Fly 992 YSDTDEDNDRTLF-------PALKEKNISTILSDLEE-------ISKDSCIG-----LDENGIEP 1037
.:.:.|.::.:.| |:..|.....:..:.|| ::::|... .:::|.|.
Human 1152 ATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEA 1216
Fly 1038 TILRKIP-------------NTPKLNEECRRSLTPVPPPGYNEEEIKKKVDCKQKP-----SFEY 1084
.:....| .|..:..|.|.|:...||.....|| ..|.::.| |.|.
Human 1217 ALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEE---PADSREPPEEPGLSQEG 1278
Fly 1085 DRIYSDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIEKSLDKNLQSPNNIVKNNNSPRNKND 1149
..:.|.....||.:.|...:.|...:.:.|...|....:...|...|..| ..||..:
Human 1279 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP-------RPPRPPS- 1335
Fly 1150 ETRKTAISQTRSCFESASKVDTTLVNIISV--ENDINEFGPHEEGDVLTNGCNKMYTNSKGKTKR 1212
...:.:||..:..|| |....:..||..| ...|..|::.
Human 1336 ---------------PPPEPETTDASHPSVPPEPLAEDHPPHTPG----------LCGSLAKSQS 1375
Fly 1213 TQS--------PVYSEGGSSQASQASQV-ALEHCYSLPPHSVSLG--------DY---------- 1250
|:: |..|.|.|..:..:.|| .....|..|..|:|.| |:
Human 1376 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS 1440
Fly 1251 ----------PSGKVNETKN----------------------------ILKREAE---------- 1267
|:|:.:|... :|:.:|.
Human 1441 GPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLP 1505
Fly 1268 -NIAIVSQMTRTGPGRPRK-----------------------------------------DPICI 1290
.:|......:..|||||: ||..:
Human 1506 APLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTV 1570
Fly 1291 QKKKRDLA------------------PRMSNVKSKMTPNGDEWP-------------------DL 1318
....|:.. |.:...|.......::|| :|
Human 1571 TLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMEL 1635
Fly 1319 AH---------KNVH------------FVPCDMYKTRDQNEEMVILYTFLTKGIDAEDINFIKMS 1362
|. |..| ..|..:::.|.:.|||.|||.....|||.|||.|:.::
Human 1636 AKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVT 1700
Fly 1363 YLDHLHKEPYAMFLNNTHWVDHCTTDRAFWPPPSKKRRKDDELIRHKTGCARTEGFYKLDVREKA 1427
|...|.::....:||:|.||.|.:|..: .:||:::||.:..|.|||||:||||.:|.::|.
Human 1701 YERLLQQDNGMDWLNDTLWVYHPSTSLS----SAKKKKRDDGIREHVTGCARSEGFYTIDKKDKL 1761
Fly 1428 KHKYHYAKANTEDSFNEDRSDEPTALTNHHHNKLISKMQGIS------------REARSNQRRLL 1480
:: .:.::|:| |||.|.| ||:| .|.||.|||||
Human 1762 RY-LNSSRAST---------DEPPADT-----------QGMSIPAQPHASTRAGSERRSEQRRLL 1805
Fly 1481 TAFGSMGESELLKFNQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRE 1545
::|....:|:||||||||||||:|||.||.||||||||||||||||||||||||.||.|:||:||
Human 1806 SSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMRE 1870
Fly 1546 TKYEAIGIGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQPIGI 1610
.:||..||||||:||:|.:||||||||||.||||||||||||||||||:||:|||||||||.|.:
Human 1871 KRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINV 1935
Fly 1611 NEEITYDYKFPLEDEKIPCLCGAQGCRGTLN 1641
|||||||||||:||.|||||||::.||||||
Human 1936 NEEITYDYKFPIEDVKIPCLCGSENCRGTLN 1966
| 
