Protein Alignment CG40160 and PRSS22

DIOPT Version :10

• Sequence 1: NP_001015212.1
• Gene: CG40160 / 3354965
• FlyBaseID: FBgn0058160
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 84/274 - (30%)
• Similarity: 127/274 - (46%)
• Gaps: 38/274 - (13%)

  Fly   148 PRGCGV-----RNTGGLDFTLSGVSQNEAGFGEFPWTVALLHSGNLSYFCAGSLIHKQVVLTAAH 207
            |..||.     |..||.|.|.|          |:||.|::..:|  ::.|||||:..:.|:||||
Human   146 PPACGKPQQLNRVVGGEDSTDS----------EWPWIVSIQKNG--THHCAGSLLTSRWVITAAH 198

  Fly   208 CVES--LRTGSFTVRAGEWDTQTMKERLPYQERSVQTVILHPDYN-RRSIAYDFALVILSQPVTL 269
            |.:.  .:...|:|..|.|.......|  .|:..|..|..||.|: :.....|.|||.|.:.:..
Human   199 CFKDNLNKPYLFSVLLGAWQLGNPGSR--SQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQF 261

  Fly   270 DDHINVICLPQQDDIPQPGNT-CFSTGWGKDAFGSLGKYSSLMKRVPLPIVEFNSC-QTRLRGTR 332
            .:.:..||||.. .|..|.|| |:.:|||....|....:...::::.:||::...| ....||..
Human   262 SERVLPICLPDA-SIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAG 325

  Fly   333 LGPKFALDRSFICAG---GQRGIDTCQGDGGAPLACPRGSTRESRYQQTGIVAWGIGCND-EVPA 393
            .||   :....:|||   |:|  |.|.||.|.||.|    ..:..:...||::||.||.: ..|.
Human   326 QGP---ITEDMLCAGYLEGER--DACLGDSGGPLMC----QVDGAWLLAGIISWGEGCAERNRPG 381

  Fly   394 AYANVALVRGWIDQ 407
            .|.:::..|.|:::
Human   382 VYISLSAHRSWVEK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40160	NP_001015212.1	CLIP_1	73..127	CDD:465709
		Tryp_SPc	166..408	CDD:238113	75/251 (30%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	80/262 (31%)