DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40160 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001015212.1	Gene:	CG40160 / 3354965	FlyBaseID:	FBgn0058160	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	282	Identity:	88/282 - (31%)
Similarity:	128/282 - (45%)	Gaps:	39/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 CG-----VRNTGGLDFTLSGVSQNEAGFGEFPWTVALLHSGNL-SYFCAGSLIHKQVVLTAAHCV 209
            ||     .|..||::          |..|.:||.|: |||... .:||.||||..:.|||||||:
Zfish    27 CGQAPLNTRIVGGVN----------ASPGSWPWQVS-LHSPKYGGHFCGGSLISSEWVLTAAHCL 80

  Fly   210 ESLRTGSFTVRAGEWDTQTMKERLPYQERSVQTVILHPDYNRRSIAYDFALVILSQPVTLDDHIN 274
            ..:...:..|..|....|.:  .:....|:|....:|..||..:...|.||:.||..||..::|.
Zfish    81 SGVSETTLVVYLGRRTQQGI--NIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIR 143

  Fly   275 VICLPQQDDIPQPGNTCFSTGWGKDAFGSLGKYSSLMKRVPLPIVEFNSCQTRL-RGTRLGPKFA 338
            .:||..|:.:...|.:.:.||||....|.......:::...:|:|..:.|...| .||
Zfish   144 PVCLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNALLGSGT------- 201

  Fly   339 LDRSFICAG-GQRGIDTCQGDGGAPLA---CPRGSTRESRYQQTGIVAWGIGCND-EVPAAYANV 398
            :..:.|||| .|.|.||||||.|.|:.   |       :.:.|.||.:||.||.| ..|..|..|
Zfish   202 VTNNMICAGLTQGGKDTCQGDSGGPMVTRLC-------TVWVQAGITSWGYGCADPNSPGVYTRV 259

  Fly   399 ALVRGWIDQQMLTNGFGTAVYT 420
            :..:.||..::..|..|..::|
Zfish   260 SQYQSWISSKISLNKPGFILFT 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40160	NP_001015212.1	Tryp_SPc	166..408	CDD:238113	80/248 (32%)
CG40160	NP_001015212.1	Tryp_SPc	169..405	CDD:214473	78/242 (32%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	82/259 (32%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587587
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930