Protein Alignment CG40160 and PRSS50

DIOPT Version :10

• Sequence 1: NP_001015212.1
• Gene: CG40160 / 3354965
• FlyBaseID: FBgn0058160
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 97/375 - (25%)
• Similarity: 146/375 - (38%)
• Gaps: 88/375 - (23%)

  Fly    53 GLVITPDPMETISQQSNFTSTSGKTATCNCVPYYKCDPSTKSFTEDGSFDGFGVIDIRFNDDDPI 117
            |.:.|.||.:...|               |||...| ||::.               |.....|
Human    45 GALSTADPADQSVQ---------------CVPKATC-PSSRP---------------RLLWQTP- 77

  Fly   118 CPASVDVCCDANRTLNKTLNPT--PLDQRPNQP-RGCGVRNTGGLDFTLSGVSQNEAGFGEFPWT 179
                      ..:||..|...|  |:.:....| |.||.  :...|.||   ...||....:||.
Human    78 ----------TTQTLPSTTMETQFPVSEGKVDPYRSCGF--SYEQDPTL---RDPEAVARRWPWM 127

  Fly   180 VALLHSGNLSYFCAGSLIHKQVVLTAAHC------VESLRTGSFTVRAGEW---DTQTMKERLPY 235
            |::..:|  ::.|||::|..|.|||.|||      :.|:|.||      .|   .|||..: :|
Human   128 VSVRANG--THICAGTIIASQWVLTVAHCLIWRDVIYSVRVGS------PWIDQMTQTASD-VP- 182

  Fly   236 QERSVQTVILHPDYNRRSI------AYDFALVILSQPVTLDDHINVICLPQQDDIPQPGNTCFST 294
                |..||:|..|..:..      |.|..|:.|.|.:...:::..||||..|.:.:..:.|..|
Human   183 ----VLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVT 243

  Fly   295 GWG-KDAFGSLGKYSSLMKRVPLPIVEFNSCQTRLRG-TRLGPKFALDRS-FICAGGQRGIDTCQ 356
            ||| ..|.|...::.::.::..: |:....|...... |::.....:.:| .:||........|.
Human   244 GWGLSKADGMWPQFRTIQEKEVI-ILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCY 307

  Fly   357 GDGGAPLACPRGSTRESRYQQTGIVAWGIGC-NDEVPAAYANVALVRGWI 405
            ...|.||.|    :.|..:...|:|:||.|| ..|.|..|..|:..:.||
Human   308 ELTGEPLVC----SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40160	NP_001015212.1	CLIP_1	73..127	CDD:465709	8/53 (15%)
		Tryp_SPc	166..408	CDD:238113	72/259 (28%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	70/253 (28%)