DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and Dnajb12

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_001361685.1	Gene:	Dnajb12 / 56709	MGIID:	1931881	Length:	378	Species:	Mus musculus

Alignment Length:	262	Identity:	52/262 - (19%)
Similarity:	110/262 - (41%)	Gaps:	40/262 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFIQIKLAYEILADLDRRRIFDRYG 94
            |.|.|||:::.|:..::::||::||.|:||||.......|.|..|..||.:|::.::|:.:|::|
Mouse   111 DYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFG 175

  Fly    95 VSDINSQYFQKKHDYSEYNR-FTLNQNDDD-----FGQRFDIKQDIAFYQKLSITENYFEKMILS 153
              |..||..:..|.:.:::| |..:.:.:|     ||..|. ..::..|....:...|.::....
Mouse   176 --DDKSQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFP-SSNVHVYSNGRMRYTYQQRQDRR 237

  Fly   154 KNAKKVHVVMFYNDWCFKCTRIVDAFKKILELLQPIGIN-FATVNAVHEESVFRKCGAREVPQLV 217
            .|.....:.:|..........:|.|..:::....|..:: ..:|..:|:.
Mouse   238 DNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKR--------------- 287

  Fly   218 LILDNQYFLYRDHSFTPQKVVEFIRKKIPFNVFKRIEHDNFNDFLGG-----WSDNRAR-ALIFE 276
                     ..||......|.:...::...:..|.:|.:..:|::..     |.:.:.: .|::.
Mouse   288 ---------VTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYR 343

  Fly   277 PR 278
            .|
Mouse   344 AR 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	23/63 (37%)
		DnaJ	30..91	CDD:278647	22/60 (37%)
		TRX_DnaJ	134..244	CDD:239261	12/110 (11%)
Dnajb12	NP_001361685.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..97
		DnaJ_bact	111..>237	CDD:274090	36/128 (28%)
		DUF1977	269..369	CDD:370429	12/101 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910