DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and DNAJC3

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	XP_011519406.1	Gene:	DNAJC3 / 5611	HGNCID:	9439	Length:	533	Species:	Homo sapiens

Alignment Length:	70	Identity:	29/70 - (41%)
Similarity:	42/70 - (60%)	Gaps:	4/70 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SSLNDPYAILGINKKATTYEIREAYKELAKKWHPDKVKND----YGAEKFIQIKLAYEILADLDR 86
            |...|.|.|||:.:.|...||.:||::||.:||||..:|:    ...:|||.|..|.|:|:|.:.
Human   419 SQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEM 483

  Fly    87 RRIFD 91
            |:.||
Human   484 RKKFD 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	28/66 (42%)
		DnaJ	30..91	CDD:278647	26/64 (41%)
		TRX_DnaJ	134..244	CDD:239261
DNAJC3	XP_011519406.1	TPR_11	36..100	CDD:290150
		TPR repeat	37..65	CDD:276809
		TPR repeat	70..100	CDD:276809
		TPR_11	73..132	CDD:290150
		TPR repeat	105..132	CDD:276809
		TPR_11	182..246	CDD:290150
		TPR repeat	186..211	CDD:276809
		TPR_11	216..281	CDD:290150
		TPR repeat	216..246	CDD:276809
		TPR repeat	251..279	CDD:276809
		TPR repeat	285..309	CDD:276809
		TPR repeat	330..364	CDD:276809
		TPR_19	347..411	CDD:291240
		TPR_1	369..402	CDD:278916
		TPR repeat	369..397	CDD:276809
		TPR repeat	403..426	CDD:276809	2/6 (33%)
		DnaJ	421..>527	CDD:223560	28/68 (41%)
		DnaJ	423..488	CDD:278647	26/64 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840