Protein Alignment l(3)80Fg and dnajc10

DIOPT Version :10

• Sequence 1: NP_001015187.2
• Gene: l(3)80Fg / 3354941
• FlyBaseID: FBgn0287183
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: NP_001077016.1
• Gene: dnajc10 / 557858
• ZFINID: ZDB-GENE-070327-1
• Length: 791
• Species: Danio rerio
• Alignment Length: 854
• Identity: 179/854 - (20%)
• Similarity: 288/854 - (33%)
• Gaps: 300/854 - (35%)

  Fly    26 SSLNDPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGA-EKFIQIKLAYEILADLDRRRI 89
            ||..|.|.:|||:::|:|.:||:|:|:||...||||..||..| :||::|..|||:|.|.|.|:.
Zfish    29 SSDEDYYKLLGISREASTRDIRQAFKKLALTMHPDKNPNDETAHDKFLKINRAYEVLKDEDLRKK 93

  Fly    90 FDRYGVSDINSQYFQKKHDYSEYNRFTLNQNDDDFGQRFDIKQDIAFYQKLSITENYFEKMILSK 154
            :|:||...:..:....:::...|.|:.....|||        .:|.     ::....|:..:
Zfish    94 YDKYGEKGLQDEQQGGRYESWNYYRYDFGIYDDD--------PEIT-----TLDRGDFDAAV--- 142

  Fly   155 NAKKVHVVMFYNDWCFKCTRIVDAFKKILELLQPIGINFATVNAVHEESVFRKCGAREVPQLVL- 218
            |:.:|..|.||...|..|..:...:::..:.:..: |....||......:.|..|....|.|.:
Zfish   143 NSGEVWFVNFYFPRCSHCHDLAPTWREFAKEMDGV-IRIGAVNCGDNGMLCRSKGINSYPSLYVF 206

  Fly   219 ---ILDNQYFLYRDHSFTPQKVVEFIRKKI----PFNVFKRIEHDNFNDFLGGWSDNRARALI-- 274
               :...:||..|..|...:..::|::.|:    ..|::..||. .|.:.: ||       ||
Zfish   207 RAGMNPEKYFNDRTKSSLTKFAMQFVKSKVTELWQGNIYSEIER-AFAERI-GW-------LITF 262

  Fly   275 -------FEPRSLTRLRYLLTAFEFYDRVAFGFVNTISKD---SSNIITRFKVNTSLDTL----- 324
                   .|.::..:|..:|.          |.||....|   .:::...|::|||...|
Zfish   263 CADTGDCLESQTRRKLAGMLD----------GLVNVGWMDCTKQADLCESFEINTSTTALFPPGS 317

  Fly   325 -------ILFNE--DTTTFTASVCMEEIPNHILVNMVSTNQFLAFPRISSQNIMESVCPTEWNRQ 380
                   :||.:  ||....|.| ::.:|:..::...|....||..|              |
Zfish   318 SLTQKGSVLFIQSLDTKEIYAQV-LQHLPDLEILTKSSFEHKLAHHR--------------W--- 364

  Fly   381 RKHLCVILITENNRKKDFE-------RVALRNIALSVG-----YNSEKVRFAYIFKESQPDFIKS 433
                   |::.:..:.|..       ...|:|..:.||     .:||.....||.|.....| |.
Zfish   365 -------LVSFSFGRNDLASHEYKKLNALLKNSHIQVGKVDCISDSELCSSLYIHKPCVAVF-KG 421

  Fly   434 ISKGSF-----KDSLIEIVIIWRRDKKRIKYNWVYVAKQNGNS-----SPEHLMNSTKD------ 482
            :....|     ||:|               ||.|..||::.|:     .||:..|..|:
Zfish   422 VGIHDFEIHHGKDAL---------------YNVVAFAKESVNAHVTTLRPENFPNHEKEPWLVDF 471

  Fly   483 -------------QISNAVKKLLKN----------SEALCYEAIVENLFNEHSQGILTKWISQFL 524
                         ::..|..:|...          .|.||      |.:|.|:          :.
Zfish   472 FAPWCPPCRALLPELRKASIQLFGQLKFGTLDCTIHEGLC------NTYNIHA----------YP 520

  Fly   525 YVVDYLSDNIEDEHLLAVFSLLGTIAFMFTVGYVLIYFVRVEEKYLKAHGHLIDIQDQRH---IN 586
            ..|.:...:|.:                             .|.:..|.|.|..|:|..:   :.
Zfish   521 TTVIFNKSSIHE-----------------------------YEGHHSADGILEFIEDLVNPVVVT 556

  Fly   587 LIPE--LKLYELRAEKYNGMVRLLKP---GCRTLL------------LIN----DCQSRH----- 625
            |.||  .:|.:.|......||....|   .|:.||            ::|    |||..|
Zfish   557 LGPESFQELVKRRKSSETWMVDFYAPWCGPCQALLPEWRRMARMLSGIVNVGTVDCQKHHSFCQS 621

  Fly   626 ---------KLIPY------------------FHKAVW-------------PYRKSKTLLFG--H 648
                     :|.|.                  |....|             |....:.:|.|  |
Zfish   622 ESVRAYPEIRLFPQNSNRRDQYQTYNGWHRDAFSLKAWALSSLPRASVDLSPEDFKRKVLGGKDH 686

  Fly   649 MVIERGLPWFAEILRLSLSKNRHLQVNPRNCVGTVLALNGHRKYFCMYHAKHPESA--------- 704
            .|::...||.....:.:    ...:|..|...|||.|    .|..|..|.:..:||
Zfish   687 WVLDFYAPWCGPCQQFA----PEFEVLARMMKGTVRA----GKVDCQAHYQTCQSAGIKAYPTVR 743

  Fly   705 ----LGTKR 709
                |||.|
Zfish   744 FYPTLGTTR 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:440252	31/64 (48%)
		TRX_DnaJ	134..244	CDD:239261	21/113 (19%)
dnajc10	NP_001077016.1	DnaJ	33..>120	CDD:440252	35/86 (41%)
		PDI_a_ERdj5_N	128..228	CDD:239301	20/108 (19%)
		Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	<276..318	CDD:469754	11/51 (22%)
		PDI_a_family	348..443	CDD:239259	25/134 (19%)
		PDI_a_ERdj5_C	450..546	CDD:239302	18/140 (13%)
		PDI_a_ERdj5_C	552..660	CDD:239302	19/107 (18%)
		PDI_a_ERdj5_C	666..772	CDD:239302	22/95 (23%)