DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and dnajc21

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_956338.1	Gene:	dnajc21 / 336984	ZFINID:	ZDB-GENE-030131-8928	Length:	545	Species:	Danio rerio

Alignment Length:	250	Identity:	62/250 - (24%)
Similarity:	107/250 - (42%)	Gaps:	76/250 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 YAILGINKKATTYEIREAYKELAKKWHPDK-VKN-DYGAEKFIQIKLAYEILADLDRRRIFDRY- 93
            |.:||:.:.|:..::::||::||.|||||| :.| :..||:|..|:.||::|:|...|..:|.:
Zfish     5 YEVLGVKRDASDDDLKKAYRKLALKWHPDKNLDNAEDAAEQFKLIQAAYDVLSDPQERAWYDNHR 69

  Fly    94 ------GVSDINSQYFQKKHDYSEYNRFTL----NQNDDDFGQRFDIKQDIAFYQKLSITENYFE 148
                  |||   .:|.....|..::  ||:    ...||:.|          ||   ::..|.||
Zfish    70 EALLKGGVS---GEYQDDSIDLVQF--FTVTCYSGYGDDEKG----------FY---AVYRNVFE 116

  Fly   149 KMILSKNAKKVH------------------------VVMFYNDWCFKCTRIVDAFKKILELLQPI 189
            .::   ..:|.|                        |.:||..|...|||...|:|:..:..|
Zfish   117 SIV---KEEKEHSKDEEDEEDEFPSFGESESDYDTVVHLFYGYWQSFCTRKNFAWKEEYDTRQ-- 176

  Fly   190 GINFATVNAVHEESVFRKCGAREVPQLVLILDNQYFLYRDHSFTPQKVVEFIRKK 244
            ..|.....|:.:|:...:..||                ::|:...:::|.|:||:
Zfish   177 ASNRWEKRAMEKENKKTRDKAR----------------KEHNELVRQLVAFVRKR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	25/70 (36%)
		DnaJ	30..91	CDD:278647	24/60 (40%)
		TRX_DnaJ	134..244	CDD:239261	26/133 (20%)
dnajc21	NP_956338.1	DnaJ	3..66	CDD:278647	24/60 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..141		2/18 (11%)
		DBINO	<183..246	CDD:290603	9/48 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..302
		zf-C2H2_jaz	323..348	CDD:288983
		C2H2 Zn finger	325..347	CDD:275371
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	331..497
		C2H2 Zn finger	500..522	CDD:275371
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..545
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592344
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930