DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and Dnajc2

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_033610.1	Gene:	Dnajc2 / 22791	MGIID:	99470	Length:	621	Species:	Mus musculus

Alignment Length:	180	Identity:	50/180 - (27%)
Similarity:	74/180 - (41%)	Gaps:	28/180 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPYAILG---INKKATTYEIREAYKELAKKWHPDKVK----------NDYGAEKFIQIKLAYEIL 81
            |.||:||   :...||..:|:.|:|.:..|.||||.|          |||    |..|..|||:|
Mouse    88 DHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDY----FTCITKAYEML 148

  Fly    82 ADLDRRRIFDRY---------GVSDINSQYFQKKHDYSEYN-RFTLNQNDDDFGQRFDIKQDI-A 135
            :|..:||.|:..         ..|:....:||......|.| |::..:|....|......:|: |
Mouse   149 SDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDA 213

  Fly   136 FYQKLSITENYFEKMILSKNAKKVHVVMFYNDWCFKCTRIVDAFKKILEL 185
            ||......:::.|...|.:..|:.........|..|..|...|.:|..|:
Mouse   214 FYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEM 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	29/85 (34%)
		DnaJ	30..91	CDD:278647	28/73 (38%)
		TRX_DnaJ	134..244	CDD:239261	12/53 (23%)
Dnajc2	NP_033610.1	ZUO1	75..368	CDD:227594	50/180 (28%)
		DnaJ	88..158	CDD:278647	28/73 (38%)
		ZRF1-UBD	160..250		16/89 (18%)
		RAC_head	349..420	CDD:293322
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	422..453
		SANT	452..508	CDD:197842
		SANT	453..506	CDD:238096
		SANT	552..602	CDD:197842
		SANT	553..600	CDD:238096
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847125
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930