DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and Dnaja1

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_001158143.1	Gene:	Dnaja1 / 15502	MGIID:	1270129	Length:	397	Species:	Mus musculus

Alignment Length:	378	Identity:	86/378 - (22%)
Similarity:	129/378 - (34%)	Gaps:	149/378 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 YAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFIQIKLAYEILADLDRRRIFDRYGVS 96
            |.:||:...||..|:::||::||.|:||||..|:  .|||.||..|||:|||..:|.::|:.|..
Mouse     8 YDVLGVKPNATQEELKKAYRKLALKYHPDKNPNE--GEKFKQISQAYEVLADSKKRELYDKGGEQ 70

  Fly    97 DINSQYFQKKHDYSEYNRFTLNQNDDDFGQRFDIKQDIAF---------------YQKLSIT-EN 145
            .|..                 ......||...|| .|:.|               ..:||:| |:
Mouse    71 AIKE-----------------GGAGGGFGSPMDI-FDMFFGGGGRMQRERRGKNVVHQLSVTLED 117

  Fly   146 YF----EKMILSKN----------AKK-----------------VH-----VVMFYNDWCFKCT- 173
            .:    .|:.|.||          .||                 :|     :|......|.:|.
Mouse   118 LYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQG 182

  Fly   174 ----------------RIVDAFKKILELLQPIGINFATVNAVHEESVFRKCGAREVP-----QLV 217
                            |.:...|||||:....|:........|.|      |.:| |     .::
Mouse   183 HGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGE------GDQE-PGLEPGDII 240

  Fly   218 LILDNQYFLYRDHSFTPQKVVEFIRKKIPFNVFKRIEHDNFN-------DFLGGWS------DNR 269
            ::||.     :||:                 ||.|...|.|.       :.|.|:.      |||
Mouse   241 IVLDQ-----KDHA-----------------VFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNR 283

  Fly   270 ARALIFEPRSLTR---LRYLLT-AFEFYDRVAFGFVNTISKDSSNIITRFKVN 318
            ...:...|..:.:   ::.:|. ....|.|         ..:...:|..||||
Mouse   284 TIVITSHPGQIVKHGDIKCVLNEGMPIYRR---------PYEKGRLIIEFKVN 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	29/61 (48%)
		DnaJ	30..91	CDD:278647	28/58 (48%)
		TRX_DnaJ	134..244	CDD:239261	31/183 (17%)
Dnaja1	NP_001158143.1	PTZ00037	2..394	CDD:240236	86/378 (23%)
		CXXCXGXG motif	134..141		0/6 (0%)
		CXXCXGXG motif	150..157		0/6 (0%)
		CXXCXGXG motif	177..184		2/6 (33%)
		CXXCXGXG motif	193..200		0/6 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..397
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910