DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and DNAJC24

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_859057.4	Gene:	DNAJC24 / 120526	HGNCID:	26979	Length:	149	Species:	Homo sapiens

Alignment Length:	168	Identity:	35/168 - (20%)
Similarity:	71/168 - (42%)	Gaps:	54/168 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGA-------EKFIQIKLAYEILADLDRR 87
            |.|:|||.:..|...::::.|::|...:||||...|..|       :|||:|..|::||.:.:.:
Human    11 DWYSILGADPSANISDLKQKYQKLILMYHPDKQSTDVPAGTVEECVQKFIEIDQAWKILGNEETK 75

  Fly    88 RIFDRY-------GVSDINSQYFQKKHDYSEYNRFTLNQNDDDF------GQRFDIKQDIAFYQK 139
            |.:|..       .|..:::|.:.::..:        |:.|..|      |.::.:.:|
Human    76 REYDLQRCEDDLRNVGPVDAQVYLEEMSW--------NEGDHSFYLSCRCGGKYSVSKD------ 126

  Fly   140 LSITENYFEKMILSKNAKKVHVVMFYNDWCFKCTRIVD 177
                           .|::|.::.     |..|:.|::
Human   127 ---------------EAEEVSLIS-----CDTCSLIIE 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	23/77 (30%)
		DnaJ	30..91	CDD:278647	22/67 (33%)
		TRX_DnaJ	134..244	CDD:239261	5/44 (11%)
DNAJC24	NP_859057.4	DnaJ	11..79	CDD:365959	22/67 (33%)
DNAJC24	NP_859057.4	zf-CSL	99..148	CDD:368338	10/80 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0715
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830