DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)80Fg and dnajc16

DIOPT Version :9

Sequence 1:	NP_001015187.2	Gene:	l(3)80Fg / 3354941	FlyBaseID:	FBgn0287183	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	XP_031761684.1	Gene:	dnajc16 / 100488071	XenbaseID:	XB-GENE-6035331	Length:	776	Species:	Xenopus tropicalis

Alignment Length:	838	Identity:	209/838 - (24%)
Similarity:	381/838 - (45%)	Gaps:	146/838 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YIITILVLCTTSYIHVCSSLN-DPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFI 72
            :.:..|||.    :.:.|:.: |||.||||:|.|:..:|::|||:||::|||||.||....:|||
Frog    11 WFLLFLVLA----LKILSAADFDPYRILGISKSASQADIKKAYKKLAREWHPDKNKNPGAEDKFI 71

  Fly    73 QIKLAYEILADLDRRRIFDRYGVSDINSQYFQKK--------HD--YSEYNRFTLNQNDDDFGQR 127
            |:..|||||::.::|..|||||....|..|.|::        ||  |.:.:.|....|.:
Frog    72 QVSKAYEILSNEEKRSNFDRYGDVGENQGYTQQQQQHHFRHFHDSFYFDESFFHFPFNSE----- 131

  Fly   128 FDIKQDIAFYQKLSITENYFEKMILSKNAKKVHVVMFYNDWCFKCTRIVDAFKKILELLQPIGIN 192
               ::|.| .:|..:..:::...::..:..|.:::...:||||.|..|...:|::::.|:.:|:.
Frog   132 ---RRDSA-DEKYLLQFSHYINEVVPDSFHKPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVG 192

  Fly   193 FATVNAVHEESVFRKCGAREVPQLVLILDNQYFLYRDHSFTPQKVVEFIRKKIPFNVFKRIEHDN 257
            ...|:|.:|..:....||...|.::.:::.:...:. ::...:.:..|:...:|.|:..:|...|
Frog   193 IGVVHAGYERRLAHHLGAHSTPSILGVINGKISFFH-NAVLRENLRHFVESLLPGNLVDKINDKN 256

  Fly   258 FNDFLGGW-SDNRARALIFEPRSLTRLRYLLTAFEFYDRVAFGFVNTISKDSSNIITRFKVNTSL 321
            :..||..| .:|:...|:|:......|.|.||||.:.|.::||:|:...:::..|.|::.:|...
Frog   257 YIRFLSNWQQENKPHVLLFDQMPPVPLIYKLTAFAYKDYLSFGYVDLGKRETEQISTQYNINMYA 321

  Fly   322 DTLILFNEDTTTFTASVCMEEIPNHILVNMVSTNQFLAFPRISSQNIMESVCPT-EWNRQRKHLC 385
            .|:::|.|........|....:...::.:.:|||:||...|:|:|.:.:.:||. :.:||||: |
Frog   322 PTILIFKEHINKPADMVQARGMKKQVIDDFISTNKFLLAARLSNQKLFQELCPVRKSHRQRKY-C 385

  Fly   386 VILITENNRKKDFERVALRNIALSVGYNSEKVRFAYIFKESQPDFIKSISKG--SFKDSLIEIVI 448
            |:|:|  ...:||::.....::.:.....:.|||...|||.|.:...::..|  .:.|.....|:
Frog   386 VVLLT--GEGEDFQKTYEAFLSFASANTKDTVRFVRAFKERQAELTSALLGGEDKYPDKPSLAVL 448

  Fly   449 IWRRDKKRIKYN-----WVYVAKQNGNSSPEHLMNSTKDQISNAVKKLLKNSEALCYEAIVENLF 508
            ..|....||.|.     |:        .|.|:     |..:.:.:.:|.|:...|..|.::.:|.
Frog   449 ERRNSAGRIVYKIVAQIWI--------GSEEN-----KFVLLDFLDRLRKDPSLLSSETVLSDLN 500

  Fly   509 NEHSQGILTKWISQFLYVVDYLSDNIED------EHLLAVFSLLGTIAFMFTVGYVLIYFVRVEE 567
            :|.:.....:|   |...:.|.|:..|.      ..::.:.||:.:..|:. .|.|::
Frog   501 DELAPVFFLRW---FYTAMHYWSEVWESLLHNNWREMMPLLSLIFSALFIL-FGTVIV------- 554

  Fly   568 KYLKAHGHLIDIQD--------------------QRHINLIPE---LKLYELRAEKYNGMVRLLK 609
               :|.....|.:|                    .:....:|:   :::.||....|...:..|:
Frog   555 ---QAFSDSSDERDSVPSDKQEPSDKEKSTETNYSKESTRVPKKGFVEVTELTDVNYMSNLVRLR 616

  Fly   610 PGCRTLLLINDCQSRHKLIPYFHKAVWPYRKSKTLLFGHMVIERGLPWFAEILR-------LSLS 667
            ||...::||....::..|:..|.:.|:.:..|.||.|..:.:|:...|...:|.       ::..
Frog   617 PGHINVVLIVSSSTKASLLQRFAQEVYTFTGSSTLHFSFLNLEKHREWLEYLLEFAQDAAPIAYQ 681

  Fly   668 KNRHLQVNPRNCVGTVLALNGHRKYFCMYHAKHPESALGTKRTLKNTQKLLDANEDPEIGTFLKR 732
            .:.|.  ..|:..|.|||||||:||||::.|                |..::..:.|
Frog   682 YDEHF--FERDYTGYVLALNGHKKYFCLFRA----------------QNTIEEEKVP-------- 720

  Fly   733 DFSEESESEPNILLEDNL---------------LNGLDNWLERLFDGRTQKYYINYWP 775
               ||.|..|  |..|:|               ||.|..|:|||.:|..|::||..||
Frog   721 ---EELELSP--LSGDSLRKMALGSGAGHIKKKLNKLSLWMERLLEGSLQRFYIPSWP 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)80Fg	NP_001015187.2	DnaJ	30..>94	CDD:223560	35/63 (56%)
		DnaJ	30..91	CDD:278647	32/60 (53%)
		TRX_DnaJ	134..244	CDD:239261	19/109 (17%)
dnajc16	XP_031761684.1	DnaJ	29..>100	CDD:223560	38/70 (54%)
dnajc16	XP_031761684.1	TRX_DnaJ	134..243	CDD:239261	20/110 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	150	1.000	Domainoid score	I4363
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H45414
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3013
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253259at2759
OrthoFinder	1	1.000	-	-		FOG0007433
OrthoInspector	1	1.000	-	-		oto102993
Panther	1	1.100	-	-	LDO	PTHR44303
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4807
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160