DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Maf1 and maf1a

DIOPT Version :9

Sequence 1:	NP_001015167.2	Gene:	Maf1 / 3354925	FlyBaseID:	FBgn0267861	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_998606.1	Gene:	maf1a / 406750	ZFINID:	ZDB-GENE-040426-2788	Length:	247	Species:	Danio rerio

Alignment Length:	232	Identity:	130/232 - (56%)
Similarity:	164/232 - (70%)	Gaps:	9/232 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLESSRFEAINNALSIQTSGITIFGRIESYSCKMVAAEKVLYKRFTADSHGHDLQALSPPQTL 65
            |||||:|.|||||:.|:|:|....|.||||||||||...:|.::|:|..:...|.|:||||||:
Zfish     1 MKLLENSSFEAINSLLTIETGDCKIIGRIESYSCKMAGDDKQMFKQFCQEGQPHVLEALSPPQS- 64

  Fly    66 ADFSPNFRRNNSQSGDEGITLCDTISRKTLFYLIATLNASFEPDYDFSEAKSHEFSKEPSLQWVM 130
            :..||| :.::|....|| .|.|..|||||||||||||.||.||||||..|.|:||||||:.||.
Zfish    65 SGISPN-KLSHSLDDGEG-PLSDKCSRKTLFYLIATLNESFRPDYDFSRTKGHDFSKEPSVNWVF 127

  Fly   131 NSIHANLSALAGDKYQAIRQPLWSAVDDEVILSECDIYSYNPDLSCDPFGEPGCLWSFNYFFYNK 195
            |:::::|||.||:.|..::..||.|:|.|:.|:|||||||||||..||:||.|.|||||||||||
Zfish   128 NAVNSSLSAAAGEAYSHLQPQLWEALDKEISLAECDIYSYNPDLDSDPYGEEGNLWSFNYFFYNK 192

  Fly   196 KLKRIVFFTSRAVNSLYA------GETLPFSMEEEVY 226
            :||||||||.|:|:...|      |..|...::|..|
Zfish   193 RLKRIVFFTCRSVSLFMAPRDSGIGTELDLELDEGSY 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Maf1	NP_001015167.2	Maf1	25..204	CDD:286283	107/178 (60%)
maf1a	NP_998606.1	Maf1	25..201	CDD:286283	107/178 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..83		11/26 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	225..247		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578998
Domainoid	1	1.000	222	1.000	Domainoid score	I2526
eggNOG	1	0.900	-	-		E1_COG5046
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49867
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3178
OMA	1	1.010	-	-		QHG55437
OrthoDB	1	1.010	-	-		D406946at33208
OrthoFinder	1	1.000	-	-		FOG0003656
OrthoInspector	1	1.000	-	-		otm25918
orthoMCL	1	0.900	-	-		OOG6_102476
Panther	1	1.100	-	-	O	PTHR22504
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1800
SonicParanoid	1	1.000	-	-		X2528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800