DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Maf1 and mafr-1

DIOPT Version :9

Sequence 1:	NP_001015167.2	Gene:	Maf1 / 3354925	FlyBaseID:	FBgn0267861	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_492777.1	Gene:	mafr-1 / 172953	WormBaseID:	WBGene00016622	Length:	245	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	75/239 - (31%)
Similarity:	109/239 - (45%)	Gaps:	47/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLESSRFEAINNALSIQTSGITIFGRIESYSCKMVAAEKVLYKR------------------- 46
            ||.||||..:..:..|........|..::|:||.|||.:||..:|.
Worm     1 MKFLESSEMDVFSQTLVTGAIDCVIDFKLETYSSKMVTSEKKQWKSNDKSVIWGERQPLGSYEEM 65

  Fly    47 -FTAD---SHGHDLQALSPPQTLADFSPNFRRNNSQSGDEGITLCDTISRKTLFYLIATLNASFE 107
             .:|.   .|.|.|:.||..........:|..|:       ..:.|:||||.|:.|...||.||
Worm    66 VMSASPSVGHNHRLRHLSERSCSGGSDNDFDVND-------YLIKDSISRKKLYDLTQVLNCSF- 122

  Fly   108 PDYDFSEAKSHEFSKEPSLQWVMNSIHANLSALAGDKYQAI-------RQPLWSAVDDEVILSEC 165
            ||:|||.|.|..|:       ::|  :::||.|...|.:.|       |:.||..:|:.::..:|
Worm   123 PDHDFSNANSEAFA-------LVN--YSDLSRLVDMKLETIVRDYHVRREELWGIIDEAIVPGDC 178

  Fly   166 DIYSYNPDLSCDPFGEPGCLWSFNYFFYNKKLKRIVFFTSRAVN 209
            .|||:......|||.|.||:|:..:.||||.|||.|..|.|.::
Worm   179 QIYSFKSQFEDDPFTEDGCIWALAFIFYNKGLKRFVLLTIRCLS 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Maf1	NP_001015167.2	Maf1	25..204	CDD:286283	66/208 (32%)
mafr-1	NP_492777.1	Maf1	25..217	CDD:286283	66/208 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166226
Domainoid	1	1.000	92	1.000	Domainoid score	I4850
eggNOG	1	0.900	-	-		E1_COG5046
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49867
Inparanoid	1	1.050	104	1.000	Inparanoid score	I3535
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55437
OrthoDB	1	1.010	-	-		D406946at33208
OrthoFinder	1	1.000	-	-		FOG0003656
OrthoInspector	1	1.000	-	-		oto18371
orthoMCL	1	0.900	-	-		OOG6_102476
Panther	1	1.100	-	-	LDO	PTHR22504
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1800
SonicParanoid	1	1.000	-	-		X2528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800