Protein Alignment Gfat1 and gfat-2

DIOPT Version :10

• Sequence 1: NP_001015157.2
• Gene: Gfat1 / 3354921
• FlyBaseID: FBgn0287209
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_502156.1
• Gene: gfat-2 / 178067
• WormBaseID: WBGene00009035
• Length: 710
• Species: Caenorhabditis elegans
• Alignment Length: 715
• Identity: 434/715 - (60%)
• Similarity: 541/715 - (75%)
• Gaps: 26/715 - (3%)

  Fly     1 MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAID-SPDNKN----IVMVKRTGKVK 60
            |||||||||:|.||.|.|::|:||.||:|:|||||||.|:||| |.|.:|    |.::::.|||.
 Worm     1 MCGIFAYLNFLAPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNDIENPHSKIALLRKRGKVS 65

  Fly    61 VLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVVHNGIITNYND 125
            ||.:.|:|:............|.|||||||||||.|.:.|||||||:|.|.|:||||||||||.:
 Worm    66 VLNDYIKENNEKLNMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDNNEFLVVHNGIITNYRE 130

  Fly   126 VKTFLSKRGYEFESDTDTEVFAKLVHHLWKTHPTYSFRELVEQAILQVEGAFAIAVKSKYFPGEC 190
            :|.:|.|:|::|||:|||||.|||..|:...:|.:|||:|||..|.|:|||||:|.||..|||:.
 Worm   131 IKEYLEKKGHKFESETDTEVIAKLTQHVHDRYPDFSFRQLVETVIQQLEGAFALAFKSSRFPGQL 195

  Fly   191 VASRRSSPLLVGIKTKTRLATDHIPILYGK------DDKKLCTDQDADSGKPQDI--------RP 241
            |||||.||||||||:.:.|.|.|.|:.|.|      ::.....::.:....|.:|        .|
 Worm   196 VASRRGSPLLVGIKSNSTLHTSHFPVSYSKGRCFMSNNATHLREETSFVETPNNILDLSIAVRNP 260

  Fly   242 HGQSRELPVLPRSESTSEFMPLEEKEVEYFFASDASAVIEHTNRVIYLEDDDVAAVRDGTLSIHR 306
            .|.::    ||.:.||:......:.|||||.||||:|:||||.:|::|||||||.|.||:|:|||
 Worm   261 SGSAK----LPDNNSTTRPFDSTDFEVEYFIASDAAAIIEHTKQVLFLEDDDVAFVEDGSLTIHR 321

  Fly   307 LKKSLDD-PHAREITTLKMEIQQIMKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIK 370
            :.:..|. ...||:..|::|||:||||:|..||||||||||:||||||||||...|. :||||:|
 Worm   322 ISRHADSGEQKREVQLLELEIQEIMKGSYKTFMQKEIFEQPESVVNTMRGRVLPSGQ-VVLGGLK 385

  Fly   371 DYIPEIKRCRRLMLIGCGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQ 435
            :|:|.|||||||:::.||||||||:|.||:||||:||||:||||||||||.|||||:|||.||||
 Worm   386 EYLPAIKRCRRLIMVACGTSYHSAIACRQVLEELSELPVVVELASDFLDRETPIFRNDVCLFISQ 450

  Fly   436 SGETADTLMALRYCKQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVM 500
            |||||||||||||||.||||.:|:||||||||.||||||:|||||||||||||||||||.:||::
 Worm   451 SGETADTLMALRYCKPRGALTIGVTNTVGSSIGRESHCGIHINAGPEIGVASTKAYTSQIVSLLL 515

  Fly   501 FALVMSEDRLSLQQRRLEILQALSKLADQIRDVLQLDSKVKELAKDLYQHKSLLIMGRGYNFATC 565
            |||.:||||:|..:||.||:.||:.|...|||||.||.:|.::|:.:|:.|||||||||.|||||
 Worm   516 FALTISEDRISKMKRRAEIIDALNNLPILIRDVLDLDDQVLKIAEQIYKDKSLLIMGRGLNFATC 580

  Fly   566 LEGALKVKELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCPI 630
            ||||||:|||:|||.||||:|||||||||:||:.:.:.|:|..|.||.|.:||||||.:|||.||
 Worm   581 LEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDHVYKKSLNALQQVVARKGAPI 645

  Fly   631 IICEEGDEETKAFSSRH-LEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLAKSVTVE 694
            ||.:....|:.....:| |.:||||||:|.||||||:||||||||.|.|.:||.|||||||||||
 Worm   646 IIADSSVPESDLAGMKHVLRVPRTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAKSVTVE 710

  Fly   695  694
             Worm   711  710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gfat1	NP_001015157.2	PLN02981	1..694	CDD:215531	432/713 (61%)
gfat-2	NP_502156.1	PLN02981	1..710	CDD:215531	432/713 (61%)