Protein Alignment Gfat1 and Gfpt1

DIOPT Version :10

• Sequence 1: NP_001015157.2
• Gene: Gfat1 / 3354921
• FlyBaseID: FBgn0287209
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: XP_036021735.1
• Gene: Gfpt1 / 14583
• MGIID: 95698
• Length: 695
• Species: Mus musculus
• Alignment Length: 707
• Identity: 447/707 - (63%)
• Similarity: 553/707 - (78%)
• Gaps: 43/707 - (6%)

  Fly     3 GIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPDNKN-------IVMVKRTGKVK 60
            ||||||||..|::|:|:|:.|:.||:|||||||||.||.:|..::|:       |.::|:.||||
Mouse    17 GIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVK 81

  Fly    61 VLEEAI---QEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVVHNGIITN 122
            .|:|.:   |:.....|:.    .|:|||||||||||.|...||||.|||..|.|:|:|||||||
Mouse    82 ALDEEVHKQQDMDLDIEFD----VHLGIAHTRWATHGEPNPVNSHPQRSDKNNEFIVIHNGIITN 142

  Fly   123 YNDVKTFLSKRGYEFESDTDTEVFAKLVHHL---WKTHPTYSFRELVEQAILQVEGAFAIAVKSK 184
            |.|:|.||..:||:|||:||||..||||.::   |::... ||..|||:.|.|:|||||:..||.
Mouse   143 YKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDV-SFTTLVERVIQQLEGAFALVFKSV 206

  Fly   185 YFPGECVASRRSSPLLVGIKTKTRLATDHIPILY--GKDDKKLCTDQDADSGKPQDIRPHGQSRE 247
            :|||:.|.:||.||||:|::::.:|:||||||||  |||.|..|.
Mouse   207 HFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTGKDKKGSCG-------------------- 251

  Fly   248 LPVLPRSESTSEFMPLEEKEVEYFFASDASAVIEHTNRVIYLEDDDVAAVRDGTLSIHRLKKSLD 312
               |.|.:||:...|:|||.|||:||||||||||||||||:|||||||||.||.|||||:|::..
Mouse   252 ---LSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAG 313

  Fly   313 DPHAREITTLKMEIQQIMKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIKDYIPEIK 377
            |...|.:.||:||:|||||||:..||||||||||:||||||||||.||...:.|||:||:|.||:
Mouse   314 DHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQ 378

  Fly   378 RCRRLMLIGCGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADT 442
            |||||:||.||||||:.|||||:|||||||||||||||||||||||:||||||||||||||||||
Mouse   379 RCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADT 443

  Fly   443 LMALRYCKQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSE 507
            ||.|||||:||||.|||||||||||.||:.|||||||||||||||||||||||:|||||||:|.:
Mouse   444 LMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCD 508

  Fly   508 DRLSLQQRRLEILQALSKLADQIRDVLQLDSKVKELAKDLYQHKSLLIMGRGYNFATCLEGALKV 572
            ||:|:|:||.||:..|.:|.|.|::||.:|.::::||.:||..||:|||||||::|||||||||:
Mouse   509 DRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKI 573

  Fly   573 KELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCPIIICEEGD 637
            ||:||||||||:|||||||||||||..|||:||::||..|.||.||||||.:|:|.|::||::.|
Mouse   574 KEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKED 638

  Fly   638 EETKAFSSRHLEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLAKSVTVE 694
            .||...:.|.:::|.:||||||||:|||:|||::|:|||||.|||.|||||||||||
Mouse   639 TETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gfat1	NP_001015157.2	PLN02981	1..694	CDD:215531	445/705 (63%)
Gfpt1	XP_036021735.1	PLN02981	17..695	CDD:215531	445/705 (63%)