Protein Alignment Dbp80 and TIF1

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_012985.3
• Gene: TIF1 / 853933
• SGDID: S000001767
• Length: 395
• Species: Saccharomyces cerevisiae
• Alignment Length: 386
• Identity: 139/386 - (36%)
• Similarity: 227/386 - (58%)
• Gaps: 31/386 - (8%)

  Fly    72 VKTFEALHLKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSR 136
            |..|:.:.|..:||:|::..||..||.||:.|:..::..  .:::||:|||||||..|.:|.|.|
Yeast    21 VYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEG--HDVLAQAQSGTGKTGTFSIAALQR 83

  Fly   137 VNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEE-VDRSKKIEE-HILIGTP 199
            ::..:..||.|.|:||.|||:|..:|...:. |..:||:...:.|.. |:.::.:.: .|::|||
Yeast    84 IDTSVKAPQALMLAPTRELALQIQKVVMALA-FHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTP 147

  Fly   200 GKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMD 264
            |::.| .|:.|.|...||.:|:|||||.|::: |..:|..:|..:|.|..|::..|||...:|::
Yeast   148 GRVFD-NIQRRRFRTDKIKMFILDEADEMLSS-GFKEQIYQIFTLLPPTTQVVLLSATMPNDVLE 210

  Fly   265 FARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAW 329
            .....:.:|..|.:.::|.:||.|||:||..:.||.||..:.::|..|||.||:|||:|:|....
Yeast   211 VTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEE 275

  Fly   330 LAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVD 394
            |..|:.:|..:|:.:..||...:|..::..||||..::||:|::|:||||::||::|:|:|||
Yeast   276 LTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLP-- 338

  Fly   395 LDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEINRSSSGAESGSREMPK 455
                |:.|.|:|||||.|||                  |:.|..||..::......||:.|
Yeast   339 ----ANKENYIHRIGRGGRF------------------GRKGVAINFVTNEDVGAMRELEK 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	69/198 (35%)
		SF2_C_DEAD	288..414	CDD:350174	55/125 (44%)
TIF1	NP_012985.3	DEAD-like_helicase_N	10..394	CDD:475120	139/386 (36%)