DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dbp80 and LOS4

DIOPT Version :9

Sequence 1:	NP_001263168.1	Gene:	Dbp80 / 3354919	FlyBaseID:	FBgn0024804	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_190879.1	Gene:	LOS4 / 824477	AraportID:	AT3G53110	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	485	Identity:	170/485 - (35%)
Similarity:	260/485 - (53%)	Gaps:	40/485 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WAKKAEDQEVSKLVDKLN-LDSKSGEETDFDVADPAETSLLIKILGKGLVNTKLSLDIQQKNPNS 67
            |....:|.:..:.|.:|| |..|..|:.|..:.:|.:::  ||.:..|               ::
plant    38 WGDVEDDDDEEEAVSELNSLSIKEEEKPDSILEEPEDSN--IKAVTSG---------------DT 85

  Fly    68 PLHSVKTFEALHLKASLLKGIYA-MGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVL 131
            |..|...||.|:|...|:||:|. |.|..|||||..:||.::..|.:::|||:.:|:|||..|||
plant    86 PYTSASRFEDLNLSPELMKGLYVEMKFEKPSKIQAISLPMIMTPPHKHLIAQAHNGSGKTTCFVL 150

  Fly   132 AMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQF---CREIKLRFAVRG-EEVDRSKKIEE 192
            .|||||:..|..||.||:.||.|||.|..||..:||:|   ..|:.:..:.|| ....|...:..
plant   151 GMLSRVDPTLREPQALCICPTRELANQNMEVLQKMGKFTGITAELAVPDSTRGAPAATRGAPVSA 215

  Fly   193 HILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHK---MLNPHCQMLFF 254
            |::|||||.|..| :.|:...:..:.:.|.||||.|:||.|..|..::|.|   .:||:.|:|.|
plant   216 HVVIGTPGTLKKW-MAFKRLGLNHLKILVFDEADHMLATDGFRDDSLKIMKDIGRVNPNFQVLLF 279

  Fly   255 SATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQN-IYGCISVGQAI 318
            |||:.:.|.||....|.||..:.:.||:.:|:::|||.|.|..|:.|...|:: |.....:||.|
plant   280 SATFNETVKDFVARTVKDPNQLFVKREDLALDSVKQYKVVCPKEQNKIEVIKDQIMELGDIGQTI 344

  Fly   319 IFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQV 383
            ||..||.:|..:...:...|:.|..:.|:||...|..::..|:..|.:|||.|::::||.|.::|
plant   345 IFVKTKASAQKVHKALAEMGYDVTSVHGNLTESDRDKIVKEFKECLTQVLIATDVIARGFDQQRV 409

  Fly   384 TIVVNFDLPVDLD-GMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEINRSSSGAE 447
            .:|||::||...: |..|.|.||||:||.|||     .|...:|.:..:.|...:.:.:.....|
plant   410 NLVVNYNLPTKYETGEPDYEVYLHRVGRAGRF-----GRKGAVFNLLLDDGWDKEVMEKIEKYFE 469

  Fly   448 SGSREMP---KEKENISLLKFFSLTGNLDE 474
            :..:|:.   .|:|..|.||   ..|.|||
plant   470 ANVKEIKSWNSEEEYKSALK---EAGLLDE 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc	75..277	CDD:238167	88/209 (42%)
		DEXDc	88..291	CDD:214692	85/210 (40%)
		Helicase_C	299..414	CDD:278689	42/116 (36%)
LOS4	NP_190879.1	PTZ00424	69..475	CDD:185609	151/428 (35%)
		P-loop_NTPase	93..302	CDD:304359	88/209 (42%)
		HELICc	313..450	CDD:238034	52/141 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	127	1.000	Domainoid score	I1766
eggNOG	1	0.900	-	-		E1_KOG0332
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	273	1.000	Inparanoid score	I907
OMA	1	1.010	-	-		QHG55249
OrthoDB	1	1.010	-	-		D608788at2759
OrthoFinder	1	1.000	-	-		FOG0001995
OrthoInspector	1	1.000	-	-		oto4028
orthoMCL	1	0.900	-	-		OOG6_101341
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1312
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840